World Journal of Emergency Surgery (Jun 2024)
Intra-abdominal infections survival guide: a position statement by the Global Alliance For Infections In Surgery
- Massimo Sartelli,
- Philip Barie,
- Vanni Agnoletti,
- Majdi N. Al-Hasan,
- Luca Ansaloni,
- Walter Biffl,
- Luis Buonomo,
- Stijn Blot,
- William G. Cheadle,
- Raul Coimbra,
- Belinda De Simone,
- Therese M. Duane,
- Paola Fugazzola,
- Helen Giamarellou,
- Timothy C. Hardcastle,
- Andreas Hecker,
- Kenji Inaba,
- Andrew W. Kirkpatrick,
- Francesco M. Labricciosa,
- Marc Leone,
- Ignacio Martin-Loeches,
- Ronald V. Maier,
- Sanjay Marwah,
- Ryan C. Maves,
- Andrea Mingoli,
- Philippe Montravers,
- Carlos A. Ordóñez,
- Miriam Palmieri,
- Mauro Podda,
- Jordi Rello,
- Robert G. Sawyer,
- Gabriele Sganga,
- Pierre Tattevin,
- Dipendra Thapaliya,
- Jeffrey Tessier,
- Matti Tolonen,
- Jan Ulrych,
- Carlo Vallicelli,
- Richard R. Watkins,
- Fausto Catena,
- Federico Coccolini
Affiliations
- Massimo Sartelli
- Department of Surgery, Macerata Hospital
- Philip Barie
- Department of Surgery, Weill Cornell Medicine
- Vanni Agnoletti
- Anesthesia and Intensive Care Unit, Bufalini Hospital - AUSL della Romagna
- Majdi N. Al-Hasan
- Department of Internal Medicine, University of South Carolina School of Medicine
- Luca Ansaloni
- Department of General and Emergency Surgery, Fondazione IRCCS San Matteo
- Walter Biffl
- Division of Trauma and Acute Care Surgery, Scripps Clinic Medical Group
- Luis Buonomo
- Emergency, Urgency and Trauma Surgery, School of Medicine, University of Buenos Aires
- Stijn Blot
- Department of Internal Medicine and Pediatrics, Faculty of Medicine and Health Sciences, Ghent University
- William G. Cheadle
- Department of Surgery, School of Medicine, University of Louisville
- Raul Coimbra
- Comparative Effectiveness and Clinical Outcomes Research Center - CECORC - Riverside University Health System
- Belinda De Simone
- Department of Surgery, Rimini “Infermi” Hospital
- Therese M. Duane
- Department of Surgery, Medical City Plano
- Paola Fugazzola
- Department of General and Emergency Surgery, Fondazione IRCCS San Matteo
- Helen Giamarellou
- First Department of Internal Medicine-Infectious Diseases, Hygeia General Hospital
- Timothy C. Hardcastle
- Department of Surgical Sciences, Nelson R Mandela School of Clinical Medicine, University of KwaZulu-Natal, and Inkosi Albert Luthuli Central Hospital
- Andreas Hecker
- Department of General and Thoracic Surgery, University Hospital of Giessen
- Kenji Inaba
- Department of Surgery, University of Southern California
- Andrew W. Kirkpatrick
- Department of Surgery and Critical Care Medicine, University of Calgary, Foothills Medical Centre
- Francesco M. Labricciosa
- Global Alliance for Infections in Surgery
- Marc Leone
- Department of Anaesthesia and Intensive Care Unit, AP-HM, Aix-Marseille University, North Hospital
- Ignacio Martin-Loeches
- Department of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organisation, St James’s Hospital
- Ronald V. Maier
- Department of Surgery, Harborview Medical Centre, University of Washington
- Sanjay Marwah
- Pandit Bhagwat Dayal Sharma Postgraduate Institute of Medical Sciences
- Ryan C. Maves
- Section of Infectious Diseases, Department of Internal Medicine, Wake Forest University School of Medicine
- Andrea Mingoli
- Emergency Department, Policlinico Umberto I, Sapienza University
- Philippe Montravers
- Anesthesiology and Critical Care Medicine Department, DMU PARABOL, Bichat Hospital, AP-HP, Université Paris Cité
- Carlos A. Ordóñez
- Division of Trauma and Acute Care Surgery, Department of Surgery, Fundación Valle del Lili
- Miriam Palmieri
- Department of Surgery, Macerata Hospital
- Mauro Podda
- Department of Surgical Science, University of Cagliari
- Jordi Rello
- Global Health eCore, Vall d’Hebron University Hospital Campus
- Robert G. Sawyer
- Department of Surgery, Western Michigan University Homer Stryker M.D. School of Medicine
- Gabriele Sganga
- Emergency Surgery and Trauma, Fondazione Policlinico Universitario A. Gemelli IRCCS
- Pierre Tattevin
- Infectious Disease and Intensive Care Unit, Pontchaillou University Hospital
- Dipendra Thapaliya
- Department of Medicine, MetroHealth Medical Center
- Jeffrey Tessier
- Division of Infectious Diseases and Geographic Medicine, University of Texas Southwestern Medical Center
- Matti Tolonen
- Emergency Surgery department, Meilahti Tower Hospital, HUS Helsinki University Hospital
- Jan Ulrych
- First Department of Surgery, Department of Abdominal, Thoracic Surgery and Traumatology, First Faculty of Medicine, Charles University and General University Hospital
- Carlo Vallicelli
- Emergency and General Surgery Department, Bufalini Hospital
- Richard R. Watkins
- Department of Medicine, Division of Infectious Diseases, Northeast Ohio Medical University
- Fausto Catena
- Emergency and General Surgery Department, Bufalini Hospital
- Federico Coccolini
- General, Emergency and Trauma Surgery Unit, Pisa University Hospital
- DOI
- https://doi.org/10.1186/s13017-024-00552-9
- Journal volume & issue
-
Vol. 19,
no. 1
pp. 1 – 20
Abstract
Abstract Intra-abdominal infections (IAIs) are an important cause of morbidity and mortality in hospital settings worldwide. The cornerstones of IAI management include rapid, accurate diagnostics; timely, adequate source control; appropriate, short-duration antimicrobial therapy administered according to the principles of pharmacokinetics/pharmacodynamics and antimicrobial stewardship; and hemodynamic and organ functional support with intravenous fluid and adjunctive vasopressor agents for critical illness (sepsis/organ dysfunction or septic shock after correction of hypovolemia). In patients with IAIs, a personalized approach is crucial to optimize outcomes and should be based on multiple aspects that require careful clinical assessment. The anatomic extent of infection, the presumed pathogens involved and risk factors for antimicrobial resistance, the origin and extent of the infection, the patient’s clinical condition, and the host’s immune status should be assessed continuously to optimize the management of patients with complicated IAIs.
Keywords
