Einstein (São Paulo) (Jun 2011)

Acute myeloid leukemia: update in diagnosis and treatment in Brazil

  • Ricardo Helman,
  • Fabio Pires de Souza Santos,
  • Belinda Simões,
  • Elias Hallack Atta,
  • Fernando Callera,
  • Jane de Almeida Dobbin,
  • Éderson Roberto Mattos,
  • Angelo Atalla,
  • Angelo Maiolino,
  • Maria Aparecida Zanichelli,
  • Cristiane Fração Diefenbach,
  • Marcia Torresan Delamain,
  • Nelson Hamerschlak

Journal volume & issue
Vol. 9, no. 2
pp. 179 – 183

Abstract

Read online

Objective: To identify how the Brazilian hematology centerstreated and diagnosed cases of acute myeloid leukemia in 2009.Methods: An epidemiological observational multicenter study of11 listed Brazilian centers that treat acute myeloid leukemia andperform bone marrow transplantation. Data were collected fromclinical charts of patients with acute myeloid leukemia treatedat the said centers between 2005 and 2009. The availability forimmunophenotyping and cytogenetic tests was assessed. Results:During 2009, a total of 345 new cases of acute myeloid leukemiawere diagnosed. Differences were noted in the tests performedbetween patients who initiated treatment at the center and thosereferred for treatment. Of the participating centers, 72% conductedsome type of molecular study in acute myeloid leukemia upondiagnosis. Conclusion: Treatment for acute myeloid leukemia inBrazil shows significantly inferior results when compared to othercenters worldwide.

Keywords