Clinical Nutrition Open Science (Aug 2022)

Undernourished patients do not have increased risk of severe COVID-19 outcomes

  • Ahmad Fneich,
  • Pierre Poinsot,
  • Christelle Elias,
  • Lioara Restier,
  • Philippe Vanhems,
  • Florent Wallet,
  • Cyrielle Caussy,
  • Antoine Duclos,
  • Noël Peretti

Journal volume & issue
Vol. 44
pp. 9 – 14

Abstract

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Background: Undernutrition has been previously identified as a deleterious factor in acute infections. In covid-19 infection, obesity is a risk-factor of severe evolution, but initial undernutrition has not been evaluated yet. Methods: We retrospectively analyzed correlation between nutritional status at admission and severe outcomes (intensive care unit admission, invasive mechanical ventilation requirement and death) of patients hospitalized for confirmed covid-19 infection. Results: Risk of intensive care unit admission and invasive mechanical ventilation requirement was not significantly different between undernutrition and normoweight sub-groups, but increased in excessive weight sub-group (ODDR (IC 95%) 1.048 (1.011-1.086), p = 0.011). Risk of death was the same in all sub-groups. Conclusion: Undernutrition didn't appear as a factor of severe outcomes in covid-19 infection.

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