Journal of Pharmacy & Pharmaceutical Sciences (May 2012)

Influence on Effectiveness of Early Treatment with Anti-TNF Therapy in Rheumatoid Arthritis

  • Vicente Escudero-Vilaplana,
  • Esther Ramírez-Herraiz,
  • Nicolás Trovato-López,
  • Estefanía Alañón-Plaza,
  • María José Bellini,
  • Ana Herranz-Alonso,
  • José María Bellón-Cano,
  • Alberto Morell-Baladrón,
  • María Sanjurjo-Sáez

DOI
https://doi.org/10.18433/J33W30
Journal volume & issue
Vol. 15, no. 3

Abstract

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Purpose. To evaluate the association between starting early treatment with anti-TNF and effectiveness as well as the possibility of applying therapeutic spacing in daily practice in patients with rheumatoid arthritis (RA). Methods. Observational, retrospective study conducted in two universitary hospitals in Spain. RA patients who received the first anti-TNF (adalimumab: ADA, etanercept: ETN or infliximab: IFX) during the study period (October 2006-2010) were included. Demographic data, time since diagnosis, disease activity (DAS28-ESR) and anti-TNF dosage were analyzed. Therapeutic objective was defined as DAS28