Emerging Infectious Diseases (Nov 2012)

Fatal Respiratory Infections Associated with Rhinovirus Outbreak, Vietnam

  • Le Thanh Hai,
  • Vu Thi Ngoc Bich,
  • Le Kien Ngai,
  • Nguyen Thi Ngoc Diep,
  • Phan Huu Phuc,
  • Viet Pham Hung,
  • Walter R. Taylor,
  • Peter Horby,
  • Nguyen Thanh Liem,
  • Heiman F.L. Wertheim

DOI
https://doi.org/10.3201/eid1811.120607
Journal volume & issue
Vol. 18, no. 11
pp. 1886 – 1888

Abstract

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During an outbreak of severe acute respiratory infections in 2 orphanages, Vietnam, 7/12 hospitalized children died. All hospitalized children and 26/43 children from outbreak orphanages tested positive for rhinovirus versus 9/40 control children (p = 0.0005). Outbreak rhinoviruses formed a distinct genetic cluster. Human rhinovirus is an underappreciated cause of severe pneumonia in vulnerable groups.

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