THE MATHEMATICAL MODELING ESTIMATION OF THE AORTIC VALVE STATE DURING MECHANICAL CIRCULATORY SUPPORT

Abstract

Aim. This work is to research the aortic valve functioning during left ventricle bypass with non-pulsatile pump.Materials and methods. The main part of the research is author’s algorithm to estimate aortic valve state (open/closed). The research includes mathematical modeling, mock loop experiments and animal experiments.Results. The author develops the algorithm of rotary blood pump fl owrate processing to estimate (with reliability of more than 90%) the state of aortic valve during heart mechanical support.Conclusion. The proposed algorithm of estimating the aortic valve state allows identifying abnormal mode of cardiac support that can cause thrombosis and aortic valve commissural fusion. This algorithm can be incorporated into nonpulsatile LVAD.

Keywords

• aortic valve
• circulatory support system
• left ventricular assist device (lvad)
• pulsation
• thrombogenesis