1358 Tissue-targeted lipid nanoparticle delivery for mRNA encoding bispecific T-cell engager demonstrated potent antitumor effects on both hematological malignancies and solid tumors

• Qi Jiang,
• Kun Huang,
• Yixin Zhang,
• Xin Kai,
• Kate Zhang,
• Benjamin Wei,
• Daniella Tatang,
• Stu Angus,
• Caining Jin,
• Changfeng Huang,
• Haishan Li,
• Qiaobing Xu

Affiliations

Qi Jiang

Freeman Spogli Institute for International Studies, Stanford University, Stanford, California, USA

Kun Huang

School of Biomedical Engineering, Shenzhen University, Shenzhen, Guangdong, China

Yixin Zhang

Department of Hepatobiliary Surgery, Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China

Xin Kai

Ragon Institute of MGH, MIT and Harvard, Cambridge Massachusetts, Massachusetts General Hospital, Harvard Medical School, Boston USA

Kate Zhang

Editas Medicine, Cambridge, MA, USA

Benjamin Wei

1Hopewell Therapeutics Inc., Woburn, MA, USA

Daniella Tatang

1Hopewell Therapeutics Inc., Woburn, MA, USA

Stu Angus

1Hopewell Therapeutics Inc., Woburn, MA, USA

Caining Jin

1Hopewell Therapeutics Inc., Woburn, MA, USA

Changfeng Huang

1Hopewell Therapeutics Inc., Woburn, MA, USA

Haishan Li

1Hopewell Therapeutics Inc., Woburn, MA, USA

Qiaobing Xu

1Hopewell Therapeutics Inc., Woburn, MA, USA