Long Noncoding RNA PRR34-AS1 Aggravates the Progression of Hepatocellular Carcinoma by Adsorbing microRNA-498 and Thereby Upregulating FOXO3 [Expression of Concern]

Abstract

Liu Z, Li Z, Xu B, Yao H, Qi S, Tai J. Cancer Manag Res. 2020;12:10749–10762. The Editor and Publisher of Cancer Management and Research wish to publish an Expression of Concern for the published article. Following publication, concerns were raised about the scientific integrity of the articles content. We reached out to the authors requesting they supply information that would confirm the integrity of the data. The authors provided several files in response to our queries but they did not satisfy our requirements to confirm the authenticity of some types of data. In addition, there were unexplained similarities between some of the figures presented in this article, and figures presented in articles by different authors groups. As yet, the authors have not provided a satisfactory explanation for this. Therefore, as we continue to work through the issues raised, we advise readers to interpret the information presented in the article with due caution. The authors have been notified about this Expression of Concern. Read the original article

Keywords

• prr34 antisense rna 1
• forkhead box o3
• cerna regulation model
• polymerase chain reaction