639 Intra-tumor delivery of IFN-alpha by Tie-2 transduced monocytes associated with favorable 2-year survival in unmethylated MGMT GBM patients: preliminary results of TEM-GBM phase 1/2a study

• Fabio Ciceri,
• Alessandro Olivi,
• Valeria Ferla,
• PAOLO FERROLI,
• Francesca Farina,
• Carlo Russo,
• Bernhard Gentner,
• Marica Eoli,
• Elena Anghileri,
• Matteo Barcella,
• Valentina Brambilla,
• Matteo Carrabba,
• Valeria Cuccarini,
• Giorgio D’Alessandris,
• Francesco Di Meco,
• Filippo Gagliardi,
• Federico Legnani,
• Stefania Mazzoleni,
• Roberto Pallini,
• Marco Saini,
• Silvia Snider,
• Karen Mullen,
• Luigi Naldini,
• Gaetano Finocchiaro

Affiliations

Fabio Ciceri

2 Vita-Salute San Raffaele University, San Raffaele Scientific Institute, Milan, Italy

Alessandro Olivi

1 Department of Neurosurgery, University Hospital Agostino Gemelli, Roma, Italy

Valeria Ferla

4Hematology and Bone Marrow Transplant Unit – San Raffaele Hospital, Milan, Italy

PAOLO FERROLI

9Neurosurgery Unit – Istituto Neurologico Carlo Besta, Milan, Italy

Francesca Farina

1Institut de Biologie Paris-Seine (IBPS), UMR 8256, Paris, France and University Hospital Department Fight Ageing and Stress, Paris, France

Carlo Russo

1Genenta Science, Princeton, NJ, USA

Bernhard Gentner

2San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, Italy

Marica Eoli

3Istituto Neurologico Carlo Besta, Milan, Italy

Elena Anghileri

3Istituto Neurologico Carlo Besta, Milan, Italy

Matteo Barcella

2San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, Italy

Valentina Brambilla

6Genenta Science, Milan, Italy

Matteo Carrabba

4Hematology and Bone Marrow Transplant Unit – San Raffaele Hospital, Milan, Italy

Valeria Cuccarini

7Neuroradiology Unit – Istituto Neurologico Carlo Besta, Milan, Italy

Giorgio D’Alessandris

8Neurosurgery Unit – Policlinico Gemelli, Rome, Italy

Francesco Di Meco

9Neurosurgery Unit – Istituto Neurologico Carlo Besta, Milan, Italy

Filippo Gagliardi

10San Raffaele Hospital, Milan, Italy

Federico Legnani

9Neurosurgery Unit – Istituto Neurologico Carlo Besta, Milan, Italy

Stefania Mazzoleni

6Genenta Science, Milan, Italy

Roberto Pallini

8Neurosurgery Unit – Policlinico Gemelli, Rome, Italy

Marco Saini

9Neurosurgery Unit – Istituto Neurologico Carlo Besta, Milan, Italy

Silvia Snider

10San Raffaele Hospital, Milan, Italy

Karen Mullen

6Genenta Science, Milan, Italy

Luigi Naldini

2San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, Italy

Gaetano Finocchiaro

11IRCCS Ospedale San Raffaele, Milano, Italy