Replication Efficiency of SARS-CoV-2 Omicron Subvariants BA.2.75, BA.5, and XBB.1 in Human Mini-Gut Organoids

• Kei Miyakawa,
• Masakazu Machida,
• Tomoyuki Kawasaki,
• Masatoshi Kakizaki,
• Yayoi Kimura,
• Masaya Sugiyama,
• Hideki Hasegawa,
• Akihiro Umezawa,
• Hidenori Akutsu,
• Akihide Ryo

Affiliations

Kei Miyakawa

Correspondence Address correspondence to: Kei Miyakawa, PhD, Research Center for Influenza and Respiratory Viruses, National Institute of Infectious Diseases, Gakuen 4-7-1, Musashimurayama, Tokyo 208-0011, Japan.; Research Center for Influenza and Respiratory Viruses, National Institute of Infectious Diseases, Tokyo, Japan; Department of Microbiology, Yokohama City University School of Medicine, Kanagawa, Japan

Masakazu Machida

Center for Regenerative Medicine, National Center for Child Health and Development, Tokyo, Japan

Tomoyuki Kawasaki

Center for Regenerative Medicine, National Center for Child Health and Development, Tokyo, Japan

Masatoshi Kakizaki

Department of Virology III, National Institute of Infectious Diseases, Tokyo, Japan

Yayoi Kimura

Advanced Medical Research Center, Yokohama City University, Kanagawa, Japan

Masaya Sugiyama

Department of Viral Pathogenesis and Controls, National Center for Global Health and Medicine, Chiba, Japan

Hideki Hasegawa

Research Center for Influenza and Respiratory Viruses, National Institute of Infectious Diseases, Tokyo, Japan

Akihiro Umezawa

Center for Regenerative Medicine, National Center for Child Health and Development, Tokyo, Japan

Hidenori Akutsu

Hidenori Akutsu, MD, PhD, Center for Regenerative Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo 157-8535, Japan.; Center for Regenerative Medicine, National Center for Child Health and Development, Tokyo, Japan

Akihide Ryo

Akihide Ryo, MD, PhD, Department of Virology III, National Institute of Infectious Diseases, Gakuen 4-7-1, Musashimurayama, Tokyo 208-0011, Japan.; Department of Microbiology, Yokohama City University School of Medicine, Kanagawa, Japan; Department of Virology III, National Institute of Infectious Diseases, Tokyo, Japan