Antimicrobial and Anti-Infective Activity of Natural Products—Gaining Knowledge from Novel Studies
Elizabeth S. Fernandes,
Isabella F. da Silva Figueiredo,
Cinara R. A. V. Monteiro,
Valério Monteiro-Neto
Affiliations
Elizabeth S. Fernandes
Programa de Pós-Graduação em Biotecnologia Aplicada à Saúde da Criança e do Adolescente, Faculdades Pequeno Príncipe, Av. Iguaçu No 333, Curitiba 80230-020, PR, Brazil
Isabella F. da Silva Figueiredo
Programa de Pós-Graduação em Biotecnologia Aplicada à Saúde da Criança e do Adolescente, Faculdades Pequeno Príncipe, Av. Iguaçu No 333, Curitiba 80230-020, PR, Brazil
Cinara R. A. V. Monteiro
Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal do Maranhão, Av. dos Portugueses No 1966, Cidade Universitária Dom Delgado, São Luís 65085-040, MA, Brazil
Valério Monteiro-Neto
Programa de Pós-Graduação em Ciências da Saúde, Universidade Federal do Maranhão, Av. dos Portugueses No 1966, Cidade Universitária Dom Delgado, São Luís 65085-040, MA, Brazil
Despite advances in the development of antimicrobial drugs in the last centuries, antimicrobial resistance has consistently raised in the last decades, compromising their effectiveness. Novel antimicrobial compounds, especially from natural sources, including plants, microorganisms, and animals, have since become a growing area of research. In this context, studies covering the investigation of their ability to combat resistant microorganisms, either by neutralization or inactivation of pathogen resistance mechanisms and virulence properties, have gained attention. Herein, a collection of 19 manuscripts focused on the antimicrobial and anti-infective activity of natural products, including their mechanisms of action, in silico evidence of antimicrobial activity, synergistic associations with antibiotics, and other aspects, will be discussed.
