DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria

Przemysław Płociński; Nigel C. Brissett; Julie Bianchi; Anna Brzostek; Małgorzata Korycka-Machała; Andrzej Dziembowski; Jarosław Dziadek; Aidan J. Doherty

doi:10.1038/s41467-017-01365-y

Nature Communications (Nov 2017)

DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria

Przemysław Płociński,
Nigel C. Brissett,
Julie Bianchi,
Anna Brzostek,
Małgorzata Korycka-Machała,
Andrzej Dziembowski,
Jarosław Dziadek,
Aidan J. Doherty

Affiliations

Przemysław Płociński: Genome Damage and Stability Centre, School of Life Sciences, University of Sussex
Nigel C. Brissett: Genome Damage and Stability Centre, School of Life Sciences, University of Sussex
Julie Bianchi: Genome Damage and Stability Centre, School of Life Sciences, University of Sussex
Anna Brzostek: Institute of Medical Biology, Polish Academy of Sciences
Małgorzata Korycka-Machała: Institute of Medical Biology, Polish Academy of Sciences
Andrzej Dziembowski: Institute of Biochemistry and Biophysics, Polish Academy of Sciences
Jarosław Dziadek: Institute of Medical Biology, Polish Academy of Sciences
Aidan J. Doherty: Genome Damage and Stability Centre, School of Life Sciences, University of Sussex

DOI: https://doi.org/10.1038/s41467-017-01365-y
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 12

Abstract

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Ligase D is a conserved DNA repair protein complex that repairs double-strand breaks in stationary phase prokaryotes. Here the authors show that orthologous Ligase C has a role in base excision repair during stationary phase.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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