Anesthesia management of CRS and HIPEC in advanced ovarian cancer with ultra-high intra-abdominal pressure: a case report

Suli Chen; Yanjun Lin; Shuncai Gao; Shuo Liu; Zhanmin Yang; Ruiqing Ma; Liangyuan Lu

doi:10.3389/fonc.2024.1449171

Frontiers in Oncology (Nov 2024)

Anesthesia management of CRS and HIPEC in advanced ovarian cancer with ultra-high intra-abdominal pressure: a case report

Suli Chen,
Yanjun Lin,
Shuncai Gao,
Shuo Liu,
Zhanmin Yang,
Ruiqing Ma,
Liangyuan Lu

Affiliations

Suli Chen: Department of Anesthesiology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, China
Yanjun Lin: Department of Anesthesiology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, China
Shuncai Gao: Department of Anesthesiology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, China
Shuo Liu: Department of Anesthesiology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, China
Zhanmin Yang: Department of Anesthesiology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, China
Ruiqing Ma: Department of Myxomatology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, China
Liangyuan Lu: Department of Anesthesiology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, Beijing, China

DOI: https://doi.org/10.3389/fonc.2024.1449171
Journal volume & issue: Vol. 14

Abstract

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Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a leading treatment for advanced ovarian cancer, significantly improving overall survival and disease-free survival. This case involves a patient with peritoneal metastasis and ultra-high intra-abdominal pressure (36 mmHg). CRS + HIPEC induces extensive pathological and physiological changes affecting respiratory, circulatory, renal, coagulation, and metabolic systems. Effective perioperative anesthesia management, including the type and volume of fluids administered, is crucial for optimizing patient outcomes. The complexities of anesthesia management in such cases present significant challenges.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

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Abstract

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