Respiratory Medicine Case Reports (Jan 2022)

A case of squamous cell lung cancer treated with anamorelin in combination with a multidisciplinary collaborative approach for treating cancer cachexia

  • Yuri Oshima,
  • Hiroyuki Matsuura,
  • Yusuke Sakurai,
  • Kaho Hirai,
  • Eriko Tani,
  • Naoki Yoshimoto,
  • Kenichi Minami,
  • Fumio Yamasaki,
  • Mayu Nishime,
  • Tomonori Hirashima

Journal volume & issue
Vol. 36
p. 101609

Abstract

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Anamorelin (ANA) is approved for treating cancer cachexia (CCX) in Japan. We report the case of a 69-year-old man with stage IVB squamous cell lung cancer complicated by CCX, having a 13.6% weight loss in 6 months. After chemotherapy was initiated, his weight was further reduced. Therefore, we started ANA combined with a treatment approach by a multidisciplinary collaboration, including nutritionists and physical therapists. After initiation of ANA, the body weight, appetite, psoas muscle index, and physical functions rapidly improved during chemotherapy. ANA administration combined with a multidisciplinary collaboration approach can be an effective supportive therapy against CCX during chemotherapy.

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