Nanotechnology Reviews (Dec 2020)

Degradable tough chitosan dressing for skin wound recovery

  • Kong Yan,
  • Tang Xiaoxuan,
  • Zhao Yahong,
  • Chen Xiaoli,
  • Yao Ke,
  • Zhang Liling,
  • Han Qi,
  • Zhang Luzhong,
  • Ling Jue,
  • Wang Yongjun,
  • Yang Yumin

DOI
https://doi.org/10.1515/ntrev-2020-0105
Journal volume & issue
Vol. 9, no. 1
pp. 1576 – 1585

Abstract

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The performance of wound dressing determines the effect of wound closure and recovery. Water absorption and bacteriostasis of wound dressings play an important role in wound recovery and healing. In this study, an optimized chitosan wound dressing-tough chitosan dressing (TCS) with high water absorption, high bacteriostasis, and degradability was developed. The chemical structure of chitosan remained stable during the process of optimized treatment, and an increase in mechanical properties was obtained for the dressing. After optimization, the water absorption and antibacterial properties of the chitosan dressing were greatly improved, which is significantly better than sodium alginate dressing. The authors believe that TCS dressing with high hygroscopicity and high bacteriostasis has great potential application value in the field of wound recovery and healing.

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