Natural Deep Eutectic Solvents as the Main Solvents for the Extraction of Total Polyphenols from Orange Peel

Abstract

The extraction of bioactive compounds is generally carried out using organic solvents, although they are very harmful to the environment. The present study focuses on the extraction of bioactive compounds using natural deep eutectic solvents (NADESs), which are novel, green, and low-melting-point solvents. In this work, we seek to optimize the extraction process of total polyphenols from orange peel using four types of NADESs with different water concentrations, solid–liquid ratios, and extraction times. The results show that the best percentage of NADESs were as follows: 10, 30, and 50%; the solid–liquid ratio differs depending on the compound, and the optimal extraction time is generally estimated to be 30 min.

Keywords

• natural deep eutectic solvents
• orange peel
• total polyphenol content