Cell Transplantation (Jul 2019)

Retrospective Case Series of Traumatic Brain Injury and Post-Traumatic Stress Disorder Treated with Hyperbaric Oxygen Therapy

  • R. Douglas Shytle,
  • David J. Eve,
  • Soel-Hee Kim,
  • Allan Spiegel,
  • Paul R. Sanberg,
  • Cesar V. Borlongan

DOI
https://doi.org/10.1177/0963689719853232
Journal volume & issue
Vol. 28

Abstract

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Returning veterans are frequently diagnosed with traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD). Considering a recent case-controlled study of hyperbaric oxygen therapy (HBOT) reporting a reduction in suicidal ideation, we investigated retrospectively three veterans with chronic TBI/PTSD symptoms who were treated with multiple rounds of HBOT with neurophysiological testing performed before and after treatment. Improvements were detected on parameters within neurocognitive domains, including reductions in suicide-related symptoms. These findings independently confirm that HBOT may be effective in treating specific symptoms of TBI/PTSD that are not currently addressed with existing therapeutic approaches.