Nature Communications (Oct 2018)

Self-induced mechanical stress can trigger biofilm formation in uropathogenic Escherichia coli

  • Eric K. Chu,
  • Onur Kilic,
  • Hojung Cho,
  • Alex Groisman,
  • Andre Levchenko

DOI
https://doi.org/10.1038/s41467-018-06552-z
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Bacterial biofilms are an increasingly important medical problem but the mechanisms by which they develop remain largely unknown. Here, using a high-throughput approach, the authors show that biofilm formation is linked to self-imposed mechanical stress.