Recent Advancements in Microneedle Technology for Multifaceted Biomedical Applications
Deepak Kulkarni,
Fouad Damiri,
Satish Rojekar,
Mehrukh Zehravi,
Sarker Ramproshad,
Dipali Dhoke,
Shubham Musale,
Ashiya A. Mulani,
Pranav Modak,
Roshani Paradhi,
Jyotsna Vitore,
Md. Habibur Rahman,
Mohammed Berrada,
Prabhanjan S. Giram,
Simona Cavalu
Affiliations
Deepak Kulkarni
Department of Pharmaceutics, Srinath College of Pharmacy, Bajajnagar, Aurangabad 431136, India
Fouad Damiri
Laboratory of Biomolecules and Organic Synthesis (BIOSYNTHO), Department of Chemistry, Faculty of Sciences Ben M’Sick, University Hassan II of Casablanca, Casablanca 20000, Morocco
Satish Rojekar
Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai 400019, India
Mehrukh Zehravi
Department of Clinical Pharmacy Girls Section, Prince Sattam Bin Abdul Aziz University, Alkharj 11942, Saudi Arabia
Sarker Ramproshad
Department of Pharmacy, Ranada Prasad Shaha University, Narayanganj 1400, Bangladesh
Dipali Dhoke
Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur 440033, India
Shubham Musale
Department of Pharmaceutics, Dr. DY Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune 411018, India
Ashiya A. Mulani
Department of Pharmaceutics, Dr. DY Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune 411018, India
Pranav Modak
Department of Pharmaceutics, Dr. DY Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune 411018, India
Roshani Paradhi
Department of Pharmaceutics, Dr. DY Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune 411018, India
Jyotsna Vitore
National Institute of Pharmaceutical Education and Research, Ahmedabad 160062, India
Md. Habibur Rahman
Department of Global Medical Science, Wonju College of Medicine, Yonsei University, Wonju 26426, Korea
Mohammed Berrada
Laboratory of Biomolecules and Organic Synthesis (BIOSYNTHO), Department of Chemistry, Faculty of Sciences Ben M’Sick, University Hassan II of Casablanca, Casablanca 20000, Morocco
Prabhanjan S. Giram
Department of Pharmaceutics, Dr. DY Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune 411018, India
Simona Cavalu
Faculty of Medicine and Pharmacy, University of Oradea, P-ta 1 Decembrie 10, 410087 Oradea, Romania
Microneedle (MNs) technology is a recent advancement in biomedical science across the globe. The current limitations of drug delivery, like poor absorption, low bioavailability, inadequate skin permeation, and poor biodistribution, can be overcome by MN-based drug delivery. Nanotechnology made significant changes in fabrication techniques for microneedles (MNs) and design shifted from conventional to novel, using various types of natural and synthetic materials and their combinations. Nowadays, MNs technology has gained popularity worldwide in biomedical research and drug delivery technology due to its multifaceted and broad-spectrum applications. This review broadly discusses MN’s types, fabrication methods, composition, characterization, applications, recent advancements, and global intellectual scenarios.
