Five-Membered Heterocyclic Ring Via Dichalcones

Abstract

ABSTRACT In this study some of dichalcone compounds (4-12) were prepared by the reaction of benzalacetone and its derivatives with a number of different ketones (acetophenone, acetanilide, 2-butanone). Also a number of heterocyclic compounds were prepared as a derivatives of that dichalcones, these derivatives were prepared by the reaction of dichalcone with hydrogen peroxide, hydrazine hydrate and urea to produce oxirane compounds (13-21), pyrazolines (22-30) and pyrimidinones (31-40) respectively. All the synthesised compounds were characterized by the available physical and spectral methods (melting point , I.R. and U.V. spectrum as well as laboratory tests). Finally the expected biological effects of some compounds were investigated.

Keywords

• five-membered heterocyclic ring
• dichalcones