Exploring Efficacy and Safety: Comparative Evaluation of Different Irrigation Solutions in Root Canal Therapy at a Tertiary Care Setting

Abstract

Background: In order to completely remove bacteria and debris from the root canal system, root canal treatment (RCT) calls for efficient irrigation methods. There is still a lack of research on the relative safety and efficacy of various irrigation systems in tertiary care settings. Methods: Patients receiving RCT at a tertiary care endodontic clinic were included in a prospective comparison research of 150 subjects. One of four irrigation solutions—sodium hypochlorite, chlorhexidine, ethylenediaminetetraacetic acid (EDTA), or a combination of the three—was given to patients at random. Following surgery, microbial decrease and patient-reported pain levels were evaluated. Results: The analysis showed that there were significant differences (P 0.05). Conclusion: Our results imply that microbial reduction in RCT is highly influenced by the irrigation solution selection. Without having an impact on the pain sensations reported by the patients, the combination of irrigation solutions showed higher efficacy in microbial control. These findings highlight how crucial it is to choose an irrigation solution carefully in order to maximize endodontic outcomes in tertiary care settings.

Keywords

• chlorhexidine
• combination therapy
• irrigation solutions
• microbial reduction
• sodium hypochlorite