Nature Communications (Mar 2022)
Tig1 regulates proximo-distal identity during salamander limb regeneration
- Catarina R. Oliveira,
- Dunja Knapp,
- Ahmed Elewa,
- Tobias Gerber,
- Sandra G. Gonzalez Malagon,
- Phillip B. Gates,
- Hannah E. Walters,
- Andreas Petzold,
- Hernan Arce,
- Rodrigo C. Cordoba,
- Elaiyaraja Subramanian,
- Osvaldo Chara,
- Elly M. Tanaka,
- András Simon,
- Maximina H. Yun
Affiliations
- Catarina R. Oliveira
- Technische Universität Dresden, CRTD/Center for Regenerative Therapies Dresden
- Dunja Knapp
- Technische Universität Dresden, CRTD/Center for Regenerative Therapies Dresden
- Ahmed Elewa
- Department of Cell and Molecular Biology, Karolinska Institute
- Tobias Gerber
- European Molecular Biology Laboratory (EMBL)
- Sandra G. Gonzalez Malagon
- Institute of Structural and Molecular Biology, University College London
- Phillip B. Gates
- Institute of Structural and Molecular Biology, University College London
- Hannah E. Walters
- Technische Universität Dresden, CRTD/Center for Regenerative Therapies Dresden
- Andreas Petzold
- Technische Universität Dresden, CRTD/Center for Regenerative Therapies Dresden
- Hernan Arce
- Systems Biology Group, Institute of Physics of Liquids and Biological Systems, National Scientific and Technical Research Council (CONICET) and University of La Plata
- Rodrigo C. Cordoba
- Systems Biology Group, Institute of Physics of Liquids and Biological Systems, National Scientific and Technical Research Council (CONICET) and University of La Plata
- Elaiyaraja Subramanian
- Department of Cell and Molecular Biology, Karolinska Institute
- Osvaldo Chara
- Systems Biology Group, Institute of Physics of Liquids and Biological Systems, National Scientific and Technical Research Council (CONICET) and University of La Plata
- Elly M. Tanaka
- Institute of Molecular Pathology, Vienna Biocenter
- András Simon
- Department of Cell and Molecular Biology, Karolinska Institute
- Maximina H. Yun
- Technische Universität Dresden, CRTD/Center for Regenerative Therapies Dresden
- DOI
- https://doi.org/10.1038/s41467-022-28755-1
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 16
Abstract
The mechanisms by which cells determine their position within the 3D space are poorly understood. Research in salamanders offers fresh insights into this question, uncovering Tig1 as a central determinant of proximo-distal identity in regeneration.
