Química Nova (Jan 2013)

Constituintes fenólicos e atividade antioxidante da geoprópolis de duas espécies de abelhas sem ferrão amazônicas

  • Ellen Cristina Costa da Silva,
  • Magno Perêa Muniz,
  • Rita de Cássia Saraiva Nunomura,
  • Sergio Massayoshi Nunomura,
  • Gislene Almeida Carvalho Zilse

DOI
https://doi.org/10.1590/S0100-40422013000500003
Journal volume & issue
Vol. 36, no. 5
pp. 628 – 633

Abstract

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We investigated the phenolic constituents and antioxidant activity of geopropolis from two species of stingless Amazonian bees, Melipona interrupta and Melipona seminigra. The chemical investigation of geopropolis from Melipona interrupta led to the isolation of 5,7,4'-trihydroxyflavonone, 3,5,6,7,4'-pentahydroxyflavonol, naringenine-4'-O-b-D-glucopyranoside and myricetin-3-O-b-D-glucopyranoside. Their structures were assigned based on spectroscopic analyses, including two-dimensional NMR techniques. Antioxidant activity of methanol and ethanol extracts of M. interrupta and M. seminigra were measured using the 1,2-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging assay. This is also the first work reporting the chemical investigation of stingless bee species from the Amazonian region.

Keywords