Nature Communications (Jan 2021)

Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition

  • E. Agirre,
  • A. J. Oldfield,
  • N. Bellora,
  • A. Segelle,
  • R. F. Luco

DOI
https://doi.org/10.1038/s41467-021-20979-x
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 16

Abstract

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Chromatin is known to regulate splicing by modulating recruitment of splicing factors. Using machine learning approaches, the authors have underlined a chromatin code for alternative splicing regulation that is conserved amongst cell lines.