Clinical, Cosmetic and Investigational Dermatology (Jun 2024)
A Comprehensive Review of Non-Surgical Treatments for Hypertrophic and Keloid Scars in Skin of Color
Abstract
Joshua Bronte,1 Crystal Zhou,1 Abhinav Vempati,1 Curtis Tam,2 Jeffrey Khong,3 Sanam Hazany,1 Salar Hazany1 1Department of Research, Scar Healing Institute, Los Angeles, CA, USA; 2Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 3Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USACorrespondence: Joshua Bronte, Scar Healing Institute, Los Angeles, CA, USA, Tel +1 424 225 2453, Email [email protected]: Hypertrophic and keloid scars are fibroproliferative growths resulting from aberrant wound healing. Individuals with Fitzpatrick skin types (FSTs) IV–VI are particularly predisposed to hypertrophic and keloid scarring, yet specific guidelines for these populations are still lacking within the literature. Therefore, this comprehensive review provides a list of various treatments and considerations for hypertrophic and keloid scarring in patients with skin of color. We constructed a comprehensive PubMed search term and performed quadruple-blinded screening on all resulting studies to achieve this objective. Our findings demonstrate 1) the lack of efficacious treatments for raised scars within this population and 2) the need to empirically investigate individualized and multimodal therapeutic options for those with skin of color.Keywords: corticosteroid, bleomycin, 5-FU, laser, FST IV-VI, skin of color
