Changes in cortical network connectivity with long-term brain-machine interface exposure after chronic amputation

Karthikeyan Balasubramanian; Mukta Vaidya; Joshua Southerland; Islam Badreldin; Ahmed Eleryan; Kazutaka Takahashi; Kai Qian; Marc W. Slutzky; Andrew H. Fagg; Karim Oweiss; Nicholas G. Hatsopoulos

doi:10.1038/s41467-017-01909-2

Nature Communications (Nov 2017)

Changes in cortical network connectivity with long-term brain-machine interface exposure after chronic amputation

Karthikeyan Balasubramanian,
Mukta Vaidya,
Joshua Southerland,
Islam Badreldin,
Ahmed Eleryan,
Kazutaka Takahashi,
Kai Qian,
Marc W. Slutzky,
Andrew H. Fagg,
Karim Oweiss,
Nicholas G. Hatsopoulos

Affiliations

Karthikeyan Balasubramanian: Department of Organismal Biology and Anatomy, University of Chicago
Mukta Vaidya: Committee on Computational Neuroscience, University of Chicago
Joshua Southerland: School of Computer Science, University of Oklahoma
Islam Badreldin: Department of Electrical & Computer Engineering, University of Florida
Ahmed Eleryan: Department of Electrical & Computer Engineering, Michigan State University
Kazutaka Takahashi: Department of Organismal Biology and Anatomy, University of Chicago
Kai Qian: Department of Biomedical Engineering, Illinois Institute of Technology
Marc W. Slutzky: Departments of Neurology, Physiology, and Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine
Andrew H. Fagg: School of Computer Science, University of Oklahoma
Karim Oweiss: Department of Electrical & Computer Engineering, University of Florida
Nicholas G. Hatsopoulos: Department of Organismal Biology and Anatomy, University of Chicago

DOI: https://doi.org/10.1038/s41467-017-01909-2
Journal volume & issue: Vol. 8, no. 1
pp. 1 – 10

Abstract

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Previous studies have shown short-term plasticity in single neurons or local field potentials during brain-machine interface (BMI) training. Here the authors report long-term changes in functional connectivity of motor cortex neuronal ensemble activity as chronically amputated monkeys learn to operate a BMI.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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