Evaluation of Selenium and Chloride levels in both sera and saliva samples in renal stone former patients

Abstract

The study included 40 patients (27 males and 13 females) with renal and ureteric stones were submitted to lithotripsy unit in Al-Yarmook Hospital, Baghdad-Iraq, their mean ages were (39±14) and 14 apparently healthy controls were enrolled in this study their mean ages were (38±12) . The study objected to evaluate the serum and saliva levels of selenium (Se) and Chloride (Cl) in patients with stones and healthy as controls to find a possible relation between these elements and stone formation. Selenium and chloride were measured both in sera and saliva, the results showed that the mean value of serum and saliva selenium levels in stone former patients were statistically significant lower compared with healthy controls (p<0.0001, 0.002) respectively, while the mean value serum chloride level in stone former patients were significantly higher than healthy controls (p< 0.018). This study showed that we can use serum and saliva selenium and serum chloride as a biomarker in renal stone former patients.

Keywords

• Urolithiasis, Selenium, Chloride.