从起步到辉煌——中国卒中临床研究发展20年 From Inception to Excellence: Two Decades of Stroke Clinical Research in China

Abstract

卒中是造成我国居民残疾和死亡的主要疾病之一，给医疗系统带来了巨大负担。循证医学研究为卒中诊疗提供了可靠的数据指导，显著降低了卒中的残疾率与死亡率。近20年来，中国临床工作者和科研人员围绕卒中诊疗的各个环节，在急性缺血性卒中再灌注治疗、卒中二级预防、脑细胞保护、血管内治疗围手术期管理、卒中诊疗质量控制与管理等重要及热点领域贡献了诸多宝贵的循证医学证据，在卒中临床研究领域发挥着越来越重要的作用。本文简要回顾了我国卒中循证医学研究的发展历程，概述了中国研究者在卒中诊疗循证实践方面的贡献与成就，并对下一阶段的卒中研究进行了展望。 Abstract: Stroke is one of the major diseases causing disability and death in Chinese residents, placing a significant burden on the healthcare system. Evidence-based medical research provides reliable data to guide stroke diagnosis and treatment, significantly reducing stroke-related disability and mortality rates. Over the past two decades, Chinese clinicist and researchers have played an increasingly prominent role in clinical research on stroke. Focusing on various aspects of stroke diagnosis and treatment, they have contributed valuable evidence-based medical evidence in major and hot fields such as reperfusion therapy for acute ischemic stroke, secondary prevention of stroke, brain cytoprotection, application of new devices and techniques, perioperative management of endovascular treatment, and quality control and management of stroke diagnosis and treatment. This article briefly reviews the development history of evidence-based medicine for stroke in China, summarizes the contributions and achievements of Chinese researchers in evidence-based practice for stroke diagnosis and treatment, and looks forward to the next phase of stroke research.

Keywords

• 循证医学
• 脑血管病
• 缺血性卒中
• 出血性卒中
• 再灌注
• 静脉溶栓
• 血管内治疗
• 二级预防
• evidence-based medicine
• cerebrovascular disease
• ischemic stroke
• hemorrhagic stroke
• reperfusion
• intravenous thrombolysis
• endovascular treatment
• secondary prevention