4,4'-Diisothiocyanato-2,2'-Stilbenedisulfonic Acid (DIDS) Modulates the Activity of KCNQ1/KCNE1 Channels by an Interaction with the Central Pore Region

• Eva Bollmann,
• Julian Alexander Schreiber,
• Nadine Ritter,
• Stefan Peischard,
• Huyen Tran Ho,
• Bernhard Wünsch,
• Timo Strünker,
• Sven Meuth,
• Thomas Budde,
• Nathalie Strutz-Seebohm,
• Guiscard Seebohm

Affiliations

Eva Bollmann

Cellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany

Julian Alexander Schreiber

Cellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany

Nadine Ritter

Cellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany; DFG Graduate School Chembion, Münster, Germany

Stefan Peischard

Cellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany

Huyen Tran Ho

Cellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany

Bernhard Wünsch

Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Münster, Germany; DFG Graduate School Chembion, Münster, Germany

Timo Strünker

DFG Graduate School Chembion, Münster, Germany; Center of Reproductive Medicine and Andrology, University Hospital Münster, Münster, Germany

Sven Meuth

DFG Graduate School Chembion, Münster, Germany; Clinic of Neurology with Institute of Translational Neurology, University Hospital Münster, Münster, Germany

Thomas Budde

DFG Graduate School Chembion, Münster, Germany; Institute of Physiology I, Westfälische Wilhelms-University, Münster, Germany

Nathalie Strutz-Seebohm

Cellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany

Guiscard Seebohm

Cellular Electrophysiology and Molecular Biology, Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany