Nature Communications (Jun 2022)
Salivary gland organoid culture maintains distinct glandular properties of murine and human major salivary glands
Abstract
The long-term maintenance of diverse salivary gland cells remains challenging. Here the authors establish a protocol for long-term maintenance of murine and human salivary gland organoids exhibiting gland-specific gene expression, gland functions, and cellular diversity confirmed by scRNA-seq.