A successful tale of sirolimus treatment in refractory vascular tumors

Abstract

Sirolimus use in vascular tumors is limited. We present two cases of refractory vascular tumors with impressive response to sirolimus, one with refractory kaposiform hemangioendothelioma with rapid reversal of thrombocytopenia and heart failure and the other with advanced beard distribution hemangioma with improvement of respiratory distress after prolonged respiratory support.

Keywords

• Sirolimus
• Kaposiform hemangioendothelioma
• Kassabach merritt phenomenon
• Infantile hemangioma