Functional analysis in a model sea anemone reveals phylogenetic complexity and a role in cnidocyte discharge of DEG/ENaC ion channels

Jose Maria Aguilar-Camacho; Katharina Foreman; Adrian Jaimes-Becerra; Reuven Aharoni; Stefan Gründer; Yehu Moran

doi:10.1038/s42003-022-04399-1

Communications Biology (Jan 2023)

Functional analysis in a model sea anemone reveals phylogenetic complexity and a role in cnidocyte discharge of DEG/ENaC ion channels

Jose Maria Aguilar-Camacho,
Katharina Foreman,
Adrian Jaimes-Becerra,
Reuven Aharoni,
Stefan Gründer,
Yehu Moran

Affiliations

Jose Maria Aguilar-Camacho: Department of Ecology, Evolution and Behavior, Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem
Katharina Foreman: Institute of Physiology, RWTH Aachen University
Adrian Jaimes-Becerra: Department of Ecology, Evolution and Behavior, Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem
Reuven Aharoni: Department of Ecology, Evolution and Behavior, Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem
Stefan Gründer: Institute of Physiology, RWTH Aachen University
Yehu Moran: Department of Ecology, Evolution and Behavior, Alexander Silberman Institute of Life Sciences, Faculty of Science, The Hebrew University of Jerusalem

DOI: https://doi.org/10.1038/s42003-022-04399-1
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 14

Abstract

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Phylogenetic analyses demonstrate a remarkable variety of the degenerin/epithelial Na+ channel (DEG/ENaC) superfamily in Cnidaria and discern an unexpected role for a proton-sensitive DEG/ENaC in N. vectensis cnidocyte discharge.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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