Clinical Ophthalmology (Sep 2014)

Acute-onset postoperative endophthalmitis caused by multidrug-resistant Klebsiella pneumoniae

  • Sanghi S,
  • Pathengay A,
  • Jindal A,
  • Raval V,
  • Nayak S,
  • Sharma S,
  • Bawdekar A,
  • Flynn HW Jr

Journal volume & issue
Vol. 2014, no. default
pp. 1783 – 1785

Abstract

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Shekhar Sanghi,1 Avinash Pathengay,1 Animesh Jindal,1 Vishal Raval,2 Sameera Nayak,2 Savitri Sharma,3 Abhishek Bawdekar,1 Harry W Flynn Jr41Department of Ophthalmology, L V Prasad Eye Institute, GMR Varalakshmi Campus, Visakhapatnam, Andhra Pradesh, India; 2Department of Ophthalmology, L V Prasad Eye Institute, KVC Campus, Vijayawada, Andhra Pradesh, India; 3Department of Microbiology, Jhaveri Microbiology Centre, L V Prasad Eye Institute, KAR Campus, Hyderabad, Andhra Pradesh, India; 4Department of Ophthalmology, Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL, USA Abstract: The purpose of this paper is to report outcomes of intravitreal imipenem in the treatment of multidrug-resistant Klebsiella-related postoperative endophthalmitis. This observational case series consists of three eyes from three patients seen between 2013 and 2014. Multidrug-resistant Klebsiella pneumoniae is characterized by a rapid, fulminant course and severe intraocular inflammation. Intravitreal imipenem may be used to treat such infection. Keywords: postoperative endophthalmitis, Klebsiella pneumoniae, imipenem, multidrug resistance