Case report of subcutaneous entomophthoromycosis with retroperitoneal invasion

Abstract

The authors describe a case of entomophthoromycosis in a previously healthy patient, who presented with an abscess in the right buttock. After surgical drainage it evolved into a retroperitoneal tumor. The patient improved clinically after resection of the mass and ketoconazole treatment. The histopathological analysis showed the Splendore-Hoeppli phenomenon, suggesting Basidiobolus ranarum infection, a zygomycosis generally restricted to the subcutaneous tissue, with rare gastrointestinal involvement.

Keywords

• Basidiobolus ranarum
• Zygomycosis
• Entomophthorales
• Clinical features
• Histopathology
• Splendore-Hoeppli phenomenon