The role of valve stiffness in the insurgence of deep vein thrombosis

Zoe Schofield; Hosam Alden Baksamawi; Joana Campos; Alessio Alexiadis; Gerard B. Nash; Alexander Brill; Daniele Vigolo

doi:10.1038/s43246-020-00066-2

Communications Materials (Sep 2020)

The role of valve stiffness in the insurgence of deep vein thrombosis

Zoe Schofield,
Hosam Alden Baksamawi,
Joana Campos,
Alessio Alexiadis,
Gerard B. Nash,
Alexander Brill,
Daniele Vigolo

Affiliations

Zoe Schofield: School of Chemical Engineering, University of Birmingham
Hosam Alden Baksamawi: School of Chemical Engineering, University of Birmingham
Joana Campos: Institute of Cardiovascular Sciences, University of Birmingham
Alessio Alexiadis: School of Chemical Engineering, University of Birmingham
Gerard B. Nash: Institute of Cardiovascular Sciences, University of Birmingham
Alexander Brill: Institute of Cardiovascular Sciences, University of Birmingham
Daniele Vigolo: School of Chemical Engineering, University of Birmingham

DOI: https://doi.org/10.1038/s43246-020-00066-2
Journal volume & issue: Vol. 1, no. 1
pp. 1 – 10

Abstract

Read online

Deep vein thrombosis is the clotting of blood in deep veins. Here, a microfluidic device containing flexible valves fabricated in-situ is used to investigate the effects of blood flow conditions and valve elasticity on thrombus formation, revealing the circumstance under which clotting occurs.

Published in Communications Materials

ISSN: 2662-4443 (Online)
Publisher: Nature Portfolio
Country of publisher: United States
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials
Website: https://www.nature.com/commsmat/

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