Cerebral Localized Marginal Zone Lymphoma Presenting as Hypothalamic-Pituitary Region Disorder

Abstract

Introduction: Marginal zone B-cell lymphoma is a rare disease which can be considerably difficult to recognize and diagnose when signs of systemic involvement are absent. Case Presentation: We report the case of a 57-year-old woman with initial olfactory disturbance, followed by psychosis, diabetes insipidus and hypothalamic eating disorder as an uncommon clinical presentation of marginal zone B-cell lymphoma. Conclusion: Marginal zone B-cell lymphoma should be considered as a potential differential diagnosis in patients with hypothalamic disturbances.

Keywords

• Bronchus-associated lymphoid tissue
• Lymphoma
• Diabetes insipidus
• Mesencephalon
• Olfactory disorder
• Symptomatic psychosis