Outcomes of in vitro fertilization pregnancies complicated by subchorionic hematoma detected on first-trimester ultrasound
Kelsey L. Anderson, M.D.,
Patricia T. Jimenez, M.D.,
Kenan R. Omurtag, M.D.,
Emily S. Jungheim, M.D., M.S.C.I.
Affiliations
Kelsey L. Anderson, M.D.
Division of Reproductive Endocrinology and Infertility, Washington University Obstetrics and Gynecology, St. Louis, Missouri
Patricia T. Jimenez, M.D.
Division of Reproductive Endocrinology and Infertility, Northwestern University Obstetrics and Gynecology, Chicago, Illinois
Kenan R. Omurtag, M.D.
Division of Reproductive Endocrinology and Infertility, Northwestern University Obstetrics and Gynecology, Chicago, Illinois
Emily S. Jungheim, M.D., M.S.C.I.
Division of Reproductive Endocrinology and Infertility, Northwestern University Obstetrics and Gynecology, Chicago, Illinois; Reprint requests: Emily S. Jungheim, M.D., M.S.C.I., Northwestern University Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, 676 North St. Clair Street, Suite 2310 Chicago, Illinois 60611
Objective: To estimate the association between subchorionic hematoma (SCH) on ultrasound and pregnancy outcomes in in vitro fertilization (IVF) pregnancies. Design: Institutional Review Board–approved, retrospective cohort study. Setting: Tertiary care university-based facility. Patient(s): In this study, 1,004 patients who underwent IVF with a viable singleton pregnancy from January 1, 2009 through December 31, 2017. Intervention(s): Subchorionic hematoma versus no hematoma diagnosed on first-trimester ultrasound. Main Outcome Measure(s): Live birth, preterm birth, and spontaneous abortion. Result(s): We found that 1,004 women met the criteria and 187 (18.6%) had an SCH. In bivariate and multivariate regression models, there were no associations between SCH and the outcomes of live birth, preterm birth, or birth weight. Conclusion(s): Subchorionic hematoma detected on first-trimester ultrasound after IVF is not associated with probability of live birth, probability of preterm birth, or infant birth weight in this patient population.
