Cannabidiol Vaping–Associated Multifocal NSCLC in a 24-Year-Old Female: A Case Report

Mansi Barthwal, MD; Nataliya Moldovan, MD; Shantanu Banerji, MD; Julian O. Kim, MD

doi:10.1016/j.jtocrr.2025.100789

JTO Clinical and Research Reports (Mar 2025)

Cannabidiol Vaping–Associated Multifocal NSCLC in a 24-Year-Old Female: A Case Report

Mansi Barthwal, MD,
Nataliya Moldovan, MD,
Shantanu Banerji, MD,
Julian O. Kim, MD

Affiliations

Mansi Barthwal, MD: Department of Radiology, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Radiation Oncology, Swami Rama Himalayan University, Dehradun, India
Nataliya Moldovan, MD: Department of Radiology, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Radiation Oncology, BC Cancer, Kelowna, British Columbia, Canada
Shantanu Banerji, MD: Department of Medical Oncology and Hematology, University of Manitoba, Winnipeg, Manitoba, Canada; Paul Albrechtsen Research Institute CancerCare Manitoba, Winnipeg, Manitoba, Canada
Julian O. Kim, MD: Department of Radiology, University of Manitoba, Winnipeg, Manitoba, Canada; Paul Albrechtsen Research Institute CancerCare Manitoba, Winnipeg, Manitoba, Canada; Corresponding author. Address for correspondence: Julian O. Kim, MD, Department of Radiology, University of Manitoba, 675 Mcdermot Ave, Winnipeg, MB R3E0V9, Canada.

DOI: https://doi.org/10.1016/j.jtocrr.2025.100789
Journal volume & issue: Vol. 6, no. 3
p. 100789

Abstract

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Vaping use among Canadian youth is rising but the long-term sequelae of cannabidiol (CBD) vaping are not yet elucidated. Vaping aerosols contain carcinogens; however, owing to the latency period between carcinogen exposure and clinical presentation of malignancies, at present, there is a paucity of reported CBD vaping–associated lung cancers. We present the case of a 24-year-old female with nonspecific respiratory symptoms who developed multifocal NSCLC attributable to extensive CBD vaping.

Published in JTO Clinical and Research Reports

ISSN: 2666-3643 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.journals.elsevier.com/jto-clinical-and-research-reports/

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