Case Reports in Medicine (Jan 2018)

A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease

  • Veeraraghavan Meyyur Aravamudan,
  • Chaozer Er,
  • Ikram Hussain,
  • Nicholas wong wai Cheong,
  • Chong Chern Hao,
  • Navin Kuthah,
  • Emily En-Xian Tan,
  • Bingwen Eugene Fan

DOI
https://doi.org/10.1155/2018/8057045
Journal volume & issue
Vol. 2018

Abstract

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Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature.