Novel antibacterial agent prepared by poly (hexamethylene guanidine hydrochloride) functionalized hollow nano-silica

ZHANG Zi-wen; ZHANG Kang-min; YANG Jian-jun; WU Qing-yun; WU Ming-yuan; ZHANG Jian-an; LIU Jiu-yi

Cailiao gongcheng (Mar 2019)

Novel antibacterial agent prepared by poly (hexamethylene guanidine hydrochloride) functionalized hollow nano-silica

ZHANG Zi-wen,
ZHANG Kang-min,
YANG Jian-jun,
WU Qing-yun,
WU Ming-yuan,
ZHANG Jian-an,
LIU Jiu-yi

Affiliations

ZHANG Zi-wen: Key Laboratory of Environment-friendly Polymer Materials of Anhui Province, School of Chemistry and Chemical Engineering, Anhui University, Hefei 230601, China
ZHANG Kang-min: Key Laboratory of Environment-friendly Polymer Materials of Anhui Province, School of Chemistry and Chemical Engineering, Anhui University, Hefei 230601, China
YANG Jian-jun: Key Laboratory of Environment-friendly Polymer Materials of Anhui Province, School of Chemistry and Chemical Engineering, Anhui University, Hefei 230601, China
WU Qing-yun: Key Laboratory of Environment-friendly Polymer Materials of Anhui Province, School of Chemistry and Chemical Engineering, Anhui University, Hefei 230601, China
WU Ming-yuan: Key Laboratory of Environment-friendly Polymer Materials of Anhui Province, School of Chemistry and Chemical Engineering, Anhui University, Hefei 230601, China
ZHANG Jian-an: Key Laboratory of Environment-friendly Polymer Materials of Anhui Province, School of Chemistry and Chemical Engineering, Anhui University, Hefei 230601, China
LIU Jiu-yi: Key Laboratory of Environment-friendly Polymer Materials of Anhui Province, School of Chemistry and Chemical Engineering, Anhui University, Hefei 230601, China

Journal volume & issue: Vol. 48, no. 3
pp. 40 – 46

Abstract

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A simple synthetic method of poly(hexamethylene guanidine hydrochloride) grafted hollow nano-silica (HSN-PHMG), a novel antibacterial material, was proposed. The water dispersibility and antibacterial property of HSN grafting of PHMG were improved. The hollow structure of nano-silica was characterized by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and thermogravimetric analysis were used to characterize the successful grafting of PHMG and the mass fraction of PHMG is about 9.5% in HSN-PHMG. Antibacterial test using Escherichia coil (E.coil) and Staphylococcus aureus (S.aureus) as test strains and the results show that the minimum inhibitory concentration (MIC) of HSN-PHMG on E.coil and S.aureus are all 32 mg/L; E.coil can be completely killed within 2 h when the concentration of HSN-PHMG is 64 mg/L.

Published in Cailiao gongcheng

ISSN: 1001-4381 (Print)
Publisher: Journal of Materials Engineering
Country of publisher: China
LCC subjects: Technology: Electrical engineering. Electronics. Nuclear engineering: Materials of engineering and construction. Mechanics of materials
Website: http://jme.biam.ac.cn/CN/1001-4381/home.shtml

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