Vaccines (Sep 2023)

Changes in Invasive Pneumococcal Disease in the Paediatric Population in the Second COVID-19 Pandemic Year

  • Conchita Izquierdo,
  • Pilar Ciruela,
  • Núria Soldevila,
  • Juan-Jose Garcia-Garcia,
  • Sebastia Gonzalez-Peris,
  • Alvaro Díaz-Conradi,
  • Belen Viñado,
  • Mariona F de Sevilla,
  • Fernando Moraga-Llop,
  • Carmen Muñoz-Almagro,
  • Angela Domínguez,
  • Barcino Working Group

DOI
https://doi.org/10.3390/vaccines11101548
Journal volume & issue
Vol. 11, no. 10
p. 1548

Abstract

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Incidence of invasive pneumococcal disease (IPD) decreased worldwide in 2020, coinciding with the implementation of measures to reduce COVID-19 transmission. We evaluated the impact of the COVID-19 pandemic on healthcare demand and IPD in children in 2021 compared to the pre-pandemic period (2018–2019) and the early pandemic period (2020) in a study carried out during 2018–2021 in Catalonia. Incidence rates were compared by calculating the incidence rate ratio (IRR), and expressing percentage changes in IRR as (1-IRR)x100. Compared to 2018–2019, emergency room (ER) visits declined by 21% in 2021 (p p p p p = 0.02) and from 0.6 to 2.1 (p=0.03) in the fourth quarter. The decreased IPD incidence observed in 2021 compared to 2018–2019 (most especially in the first quarter) was greater than the decrease in healthcare demand and PCR test requests. Compared to 2020, IPD incidence decreased in the first quarter when a second state of alarm was in force. In 2021, compared to 2018–2019, there was a greater reduction in PCV13 serotypes than in non-PCV13 serotypes.

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