Cold-chain-based epidemiology: Scientific evidence and logic in introduction and transmission of SARS-CoV-2

Ying Lin; Xiaozhou He; Wenwen Lei; Zhiyuan Jia; Jue Liu; Cunrui Huang; Jingkun Jiang; Qihui Wang; Fengqin Li; Wei Ma; Min Liu; George F. Gao; Guizhen Wu; Jun Liu

Global Transitions (Jan 2023)

Cold-chain-based epidemiology: Scientific evidence and logic in introduction and transmission of SARS-CoV-2

Ying Lin,
Xiaozhou He,
Wenwen Lei,
Zhiyuan Jia,
Jue Liu,
Cunrui Huang,
Jingkun Jiang,
Qihui Wang,
Fengqin Li,
Wei Ma,
Min Liu,
George F. Gao,
Guizhen Wu,
Jun Liu

Affiliations

Ying Lin: School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China; National Health Commission Key Laboratory of Biosafety, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), Research Unit of Adaptive Evolution and Control of Emerging Viruses, Chinese Academy of Medical Sciences, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China
Xiaozhou He: National Health Commission Key Laboratory of Biosafety, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), Research Unit of Adaptive Evolution and Control of Emerging Viruses, Chinese Academy of Medical Sciences, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China
Wenwen Lei: National Health Commission Key Laboratory of Biosafety, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), Research Unit of Adaptive Evolution and Control of Emerging Viruses, Chinese Academy of Medical Sciences, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China
Zhiyuan Jia: National Health Commission Key Laboratory of Biosafety, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), Research Unit of Adaptive Evolution and Control of Emerging Viruses, Chinese Academy of Medical Sciences, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China
Jue Liu: School of Public Health, Peking University, Beijing, 100191, China
Cunrui Huang: Vanke School of Public Health, Tsinghua University, Beijing, 100084, China
Jingkun Jiang: School of Environment, Tsinghua University, Beijing, 100084, China
Qihui Wang: CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, 100101, China
Fengqin Li: NHC Key Laboratory of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, Beijing, 100021, China
Wei Ma: School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China
Min Liu: School of Public Health, Peking University, Beijing, 100191, China
George F. Gao: School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China; National Health Commission Key Laboratory of Biosafety, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), Research Unit of Adaptive Evolution and Control of Emerging Viruses, Chinese Academy of Medical Sciences, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China; CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, 100101, China; Corresponding author. School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, 250012, China.
Guizhen Wu: National Health Commission Key Laboratory of Biosafety, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), Research Unit of Adaptive Evolution and Control of Emerging Viruses, Chinese Academy of Medical Sciences, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China; Corresponding author.
Jun Liu: National Health Commission Key Laboratory of Biosafety, National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), Research Unit of Adaptive Evolution and Control of Emerging Viruses, Chinese Academy of Medical Sciences, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China; Corresponding author.

Journal volume & issue: Vol. 5
pp. 170 – 181

Abstract

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During the COVID-19 pandemic, a series of outbreaks and related investigations have indicated that the virus can be transmitted via cold-chain environment media. The causal relationship between the cold chain and the introduction and spread of viruses has been established. However, due to its stealthy nature, cold-chain environment media is often overlooked. Herein, we aim to provide a systematic review of the existing evidences and logical chains of virus transmission and introduction through cold-chain, from the perspectives of epidemiological investigations, laboratory researches, and molecular epidemiological evidences of cold-chain-related outbreaks. Additionally, scientific evidences also include the survival capacity of the virus in cold-chain environments, as well as modeling of virus transmission and risk assessment. These evidences and the logical framework related to cold-chain transmission put forward the initiation of cold-chain-based epidemiology (CCBE) as one of the important portions of the epidemiology of infectious diseases. Close multidisciplinary collaboration in this field will be essential for the preparation of future pandemics.

Published in Global Transitions

ISSN: 2589-7918 (Online)
Publisher: KeAi Communications Co., Ltd.
Country of publisher: China
LCC subjects: Technology; Medicine
Website: https://www.keaipublishing.com/en/journals/global-transitions/

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