Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections

Haya Al-Sulaiti; Jehad Almaliti; C. Benjamin Naman; Asmaa A. Al Thani; Hadi M. Yassine

doi:10.3390/metabo13080948

Metabolites (Aug 2023)

Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections

Haya Al-Sulaiti,
Jehad Almaliti,
C. Benjamin Naman,
Asmaa A. Al Thani,
Hadi M. Yassine

Affiliations

Haya Al-Sulaiti: QU Health, Qatar University, Doha P.O. Box 2713, Qatar
Jehad Almaliti: Scripps Institution of Oceanography, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA P.O. Box 92093, USA
C. Benjamin Naman: Department of Science and Conservation, San Diego Botanic Garden, Encinitas, CA P.O. Box 92024, USA
Asmaa A. Al Thani: QU Health, Qatar University, Doha P.O. Box 2713, Qatar
Hadi M. Yassine: Biomedical Research Center, Qatar University, Doha P.O. Box 2713, Qatar

DOI: https://doi.org/10.3390/metabo13080948
Journal volume & issue: Vol. 13, no. 8
p. 948

Abstract

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Metabolomics is an analytical approach that involves profiling and comparing the metabolites present in biological samples. This scoping review article offers an overview of current metabolomics approaches and their utilization in evaluating metabolic changes in biological fluids that occur in response to viral infections. Here, we provide an overview of metabolomics methods including high-throughput analytical chemistry and multivariate data analysis to identify the specific metabolites associated with viral infections. This review also focuses on data interpretation and applications designed to improve our understanding of the pathogenesis of these viral diseases.

Published in Metabolites

ISSN: 2218-1989 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Microbiology
Website: http://www.mdpi.com/journal/metabolites

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Abstract

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