Huge Dedifferentiated Liposarcoma of the Left Thigh with a High Grade Fibrosarcomatous Differentiation and a Local Recurrence

Abstract

Dedifferentiated liposarcoma is one of the variants of liposarcoma which has a more aggressive course. It constitutes less than 10% of all the liposarcomas and is often found in the retroperitoneum and the mediastinum. We are reporting a rare case of a 60 years old female who presented with a huge, soft tissue mass in the left thigh with a past history of an operation which was done15 years back. The histopathological examination showed a well differentiated liposarcoma with a high grade fibrosarcomatous differentiation. Immunohistochemical studies confirmed the dedifferentiated liposarcoma with the high grade fibrosarcomatous differentiation. To the best of our knowledge, this is the 11th case in the literature with rare findings.

Keywords

• dedifferentiated liposarcoma
• fibrosarcoma
• well differentiated liposarcoma
• soft tissue tumours