Human Vaccines & Immunotherapeutics (Jan 2022)

“Titer of anti-HBs in health professions trainees: prevalence of antibody coverage in a University of Central Italy”

  • Luca Di Giampaolo,
  • Erica Costantini,
  • Marta Di Nicola,
  • Annamaria Porreca,
  • Gioele D’Amore,
  • Luca Coppeta,
  • Rocco Mangifesta

DOI
https://doi.org/10.1080/21645515.2021.1886805
Journal volume & issue
Vol. 18, no. 1

Abstract

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Objective This observational retrospective study aims at verifying hepatitis-B-virus (HBV) vaccination coverage in students vaccinated before and after 1992, in order to optimize health surveillance and vaccination recall. Methods Vaccination status was evaluated using the anti-HBs antibody titer (anti-HBs). Student t-test and the chi-square test were performed to identify the average age and the difference in antibody coverage between the two genders and in the two populations analyzed. Results Our study outlined a prevalence of 21.83% uncovered trainees among those vaccinated at age 12 and 45.03% among those vaccinated in neonatal age. Conclusion In conclusion, our data showed persistent protection against HBV infection in healthcare students.

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