Reaction Mechanism and Substrate Specificity of Iso-orotate Decarboxylase: A Combined Theoretical and Experimental Study

• Xiang Sheng,
• Katharina Plasch,
• Stefan E. Payer,
• Claudia Ertl,
• Gerhard Hofer,
• Walter Keller,
• Simone Braeuer,
• Walter Goessler,
• Silvia M. Glueck,
• Silvia M. Glueck,
• Fahmi Himo,
• Kurt Faber

Affiliations

Xiang Sheng

Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden

Katharina Plasch

Institute of Chemistry, Organic & Bioorganic Chemistry, University of Graz, Graz, Austria

Stefan E. Payer

Institute of Chemistry, Organic & Bioorganic Chemistry, University of Graz, Graz, Austria

Claudia Ertl

Institute of Chemistry, Organic & Bioorganic Chemistry, University of Graz, Graz, Austria

Gerhard Hofer

Institute of Molecular Biosciences, University of Graz, Graz, Austria

Walter Keller

Institute of Molecular Biosciences, University of Graz, Graz, Austria

Simone Braeuer

Institute of Chemistry, Analytical Chemistry, University of Graz, Graz, Austria

Walter Goessler

Institute of Chemistry, Analytical Chemistry, University of Graz, Graz, Austria

Silvia M. Glueck

Institute of Chemistry, Organic & Bioorganic Chemistry, University of Graz, Graz, Austria

Silvia M. Glueck

Austrian Centre of Industrial Biotechnology (ACIB GmbH), Graz, Austria

Fahmi Himo

Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Stockholm, Sweden

Kurt Faber

Institute of Chemistry, Organic & Bioorganic Chemistry, University of Graz, Graz, Austria