Journal of Investigative Medicine High Impact Case Reports (Jul 2021)

Complete Response With Immunotherapy: A Case of Metastatic Bladder Cancer

  • Balraj Singh MD,
  • Parminder Kaur MD,
  • Sachin Gupta MD,
  • Nirmal Guragai MD,
  • Michael Maroules MD

DOI
https://doi.org/10.1177/23247096211035603
Journal volume & issue
Vol. 9

Abstract

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Bladder cancer is the most common urinary tract malignancy. Platinum-based chemotherapy is the first line of treatment in locally advanced or metastatic bladder cancer. Immunotherapy has become a novel therapy option in a broad variety of malignancies including bladder cancer. Immunotherapy is approved as first line of treatment in patients who are ineligible for platinum-based chemotherapy and second-line treatment for metastatic urothelial cancer who progressed after platinum-based treatments. We present the case of an 83-year-old female with metastatic bladder cancer who was chemotherapy ineligible and had complete response with immune checkpoint inhibitor pembrolizumab.