EPILEPTIC ENCEPHALOPTHIES WITH ELECTRICAL STATUS EPILEPTICUS SLOW SLEEP (ESES)

Abstract

Complex of acquired disturbances of cognitive functions in children associated with continuous epileptiform activity on the EEG is a serious problem. Quite often the EEG patterns in epileptic encephalopathies of childhood such as Landau-Kleffner, pseudo-Lennox syndromes, autistic epileptiform regression etc. are represented by the so-called «benign focal epileptiform discharges of childhood» (BEDOC, BFEDC, BEDC). Epileptiform discharges are characterized by high index and diffuse spreading nature, especially during slow-wave sleep, forming the pattern of ESES. In the treatment of epileptic encephalopathies the following AEDs are applied in monotherapy or rational combined therapy: valproates, ethosuximide, levetiracetam, sultiame and benzodiazepines.

Keywords

• epileptic encephalopathies
• epilepsy with electrical status epilepticus during slow sleep (eses)
• antiepileptic drugs (aed)