Nature Communications (Apr 2016)
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
- Fergus J. Couch,
- Karoline B. Kuchenbaecker,
- Kyriaki Michailidou,
- Gustavo A. Mendoza-Fandino,
- Silje Nord,
- Janna Lilyquist,
- Curtis Olswold,
- Emily Hallberg,
- Simona Agata,
- Habibul Ahsan,
- Kristiina Aittomäki,
- Christine Ambrosone,
- Irene L. Andrulis,
- Hoda Anton-Culver,
- Volker Arndt,
- Banu K. Arun,
- Brita Arver,
- Monica Barile,
- Rosa B. Barkardottir,
- Daniel Barrowdale,
- Lars Beckmann,
- Matthias W. Beckmann,
- Javier Benitez,
- Stephanie V. Blank,
- Carl Blomqvist,
- Natalia V. Bogdanova,
- Stig E. Bojesen,
- Manjeet K. Bolla,
- Bernardo Bonanni,
- Hiltrud Brauch,
- Hermann Brenner,
- Barbara Burwinkel,
- Saundra S. Buys,
- Trinidad Caldes,
- Maria A. Caligo,
- Federico Canzian,
- Jane Carpenter,
- Jenny Chang-Claude,
- Stephen J. Chanock,
- Wendy K. Chung,
- Kathleen B. M. Claes,
- Angela Cox,
- Simon S. Cross,
- Julie M. Cunningham,
- Kamila Czene,
- Mary B. Daly,
- Francesca Damiola,
- Hatef Darabi,
- Miguel de la Hoya,
- Peter Devilee,
- Orland Diez,
- Yuan C. Ding,
- Riccardo Dolcetti,
- Susan M. Domchek,
- Cecilia M. Dorfling,
- Isabel dos-Santos-Silva,
- Martine Dumont,
- Alison M. Dunning,
- Diana M. Eccles,
- Hans Ehrencrona,
- Arif B. Ekici,
- Heather Eliassen,
- Steve Ellis,
- Peter A. Fasching,
- Jonine Figueroa,
- Dieter Flesch-Janys,
- Asta Försti,
- Florentia Fostira,
- William D. Foulkes,
- Tara Friebel,
- Eitan Friedman,
- Debra Frost,
- Marike Gabrielson,
- Marilie D. Gammon,
- Patricia A. Ganz,
- Susan M. Gapstur,
- Judy Garber,
- Mia M. Gaudet,
- Simon A. Gayther,
- Anne-Marie Gerdes,
- Maya Ghoussaini,
- Graham G. Giles,
- Gord Glendon,
- Andrew K. Godwin,
- Mark S. Goldberg,
- David E. Goldgar,
- Anna González-Neira,
- Mark H. Greene,
- Jacek Gronwald,
- Pascal Guénel,
- Marc Gunter,
- Lothar Haeberle,
- Christopher A. Haiman,
- Ute Hamann,
- Thomas V. O. Hansen,
- Steven Hart,
- Sue Healey,
- Tuomas Heikkinen,
- Brian E. Henderson,
- Josef Herzog,
- Frans B. L. Hogervorst,
- Antoinette Hollestelle,
- Maartje J. Hooning,
- Robert N. Hoover,
- John L. Hopper,
- Keith Humphreys,
- David J. Hunter,
- Tomasz Huzarski,
- Evgeny N. Imyanitov,
- Claudine Isaacs,
- Anna Jakubowska,
- Paul James,
- Ramunas Janavicius,
- Uffe Birk Jensen,
- Esther M. John,
- Michael Jones,
- Maria Kabisch,
- Siddhartha Kar,
- Beth Y. Karlan,
- Sofia Khan,
- Kay-Tee Khaw,
- Muhammad G. Kibriya,
- Julia A. Knight,
- Yon-Dschun Ko,
- Irene Konstantopoulou,
- Veli-Matti Kosma,
- Vessela Kristensen,
- Ava Kwong,
- Yael Laitman,
- Diether Lambrechts,
- Conxi Lazaro,
- Eunjung Lee,
- Loic Le Marchand,
- Jenny Lester,
- Annika Lindblom,
- Noralane Lindor,
- Sara Lindstrom,
- Jianjun Liu,
- Jirong Long,
- Jan Lubinski,
- Phuong L. Mai,
- Enes Makalic,
- Kathleen E. Malone,
- Arto Mannermaa,
- Siranoush Manoukian,
- Sara Margolin,
- Frederik Marme,
- John W. M. Martens,
- Lesley McGuffog,
- Alfons Meindl,
- Austin Miller,
- Roger L. Milne,
- Penelope Miron,
- Marco Montagna,
- Sylvie Mazoyer,
- Anna M. Mulligan,
- Taru A. Muranen,
- Katherine L. Nathanson,
- Susan L. Neuhausen,
- Heli Nevanlinna,
- Børge G. Nordestgaard,
- Robert L. Nussbaum,
- Kenneth Offit,
- Edith Olah,
- Olufunmilayo I. Olopade,
- Janet E. Olson,
- Ana Osorio,
- Sue K. Park,
- Petra H. Peeters,
- Bernard Peissel,
- Paolo Peterlongo,
- Julian Peto,
- Catherine M. Phelan,
- Robert Pilarski,
- Bruce Poppe,
- Katri Pylkäs,
- Paolo Radice,
- Nazneen Rahman,
- Johanna Rantala,
- Christine Rappaport,
- Gad Rennert,
- Andrea Richardson,
- Mark Robson,
- Isabelle Romieu,
- Anja Rudolph,
- Emiel J. Rutgers,
- Maria-Jose Sanchez,
- Regina M. Santella,
- Elinor J. Sawyer,
- Daniel F. Schmidt,
- Marjanka K. Schmidt,
- Rita K. Schmutzler,
- Fredrick Schumacher,
- Rodney Scott,
- Leigha Senter,
- Priyanka Sharma,
- Jacques Simard,
- Christian F. Singer,
- Olga M. Sinilnikova,
- Penny Soucy,
- Melissa Southey,
- Doris Steinemann,
- Marie Stenmark-Askmalm,
- Dominique Stoppa-Lyonnet,
- Anthony Swerdlow,
- Csilla I. Szabo,
- Rulla Tamimi,
- William Tapper,
- Manuel R. Teixeira,
- Soo-Hwang Teo,
- Mary B. Terry,
- Mads Thomassen,
- Deborah Thompson,
- Laima Tihomirova,
- Amanda E. Toland,
- Robert A. E. M. Tollenaar,
- Ian Tomlinson,
- Thérèse Truong,
- Helen Tsimiklis,
- Alex Teulé,
- Rosario Tumino,
- Nadine Tung,
- Clare Turnbull,
- Giski Ursin,
- Carolien H. M. van Deurzen,
- Elizabeth J. van Rensburg,
- Raymonda Varon-Mateeva,
- Zhaoming Wang,
- Shan Wang-Gohrke,
- Elisabete Weiderpass,
- Jeffrey N. Weitzel,
- Alice Whittemore,
- Hans Wildiers,
- Robert Winqvist,
- Xiaohong R. Yang,
- Drakoulis Yannoukakos,
- Song Yao,
- M Pilar Zamora,
- Wei Zheng,
- Per Hall,
- Peter Kraft,
- Celine Vachon,
- Susan Slager,
- Georgia Chenevix-Trench,
- Paul D. P. Pharoah,
- Alvaro A. N. Monteiro,
- Montserrat García-Closas,
- Douglas F. Easton,
- Antonis C. Antoniou
Affiliations
- Fergus J. Couch
- Department of Laboratory Medicine and Pathology, Mayo Clinic
- Karoline B. Kuchenbaecker
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Kyriaki Michailidou
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Gustavo A. Mendoza-Fandino
- Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute
- Silje Nord
- Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet
- Janna Lilyquist
- Department of Health Sciences Research, Mayo Clinic
- Curtis Olswold
- Department of Health Sciences Research, Mayo Clinic
- Emily Hallberg
- Department of Health Sciences Research, Mayo Clinic
- Simona Agata
- Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV—IRCCS
- Habibul Ahsan
- Department of Health Studies, The University of Chicago
- Kristiina Aittomäki
- Department of Clinical Genetics, Helsinki University Central Hospital
- Christine Ambrosone
- Department of Cancer Prevention and Control, Roswell Park Cancer Institute
- Irene L. Andrulis
- Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital
- Hoda Anton-Culver
- Department of Epidemiology, University of California Irvine
- Volker Arndt
- Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)
- Banu K. Arun
- University of Texas MD Anderson Cancer Center
- Brita Arver
- Department of Oncology, Karolinska University Hospital
- Monica Barile
- Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia
- Rosa B. Barkardottir
- Department of Pathology, Landspitali University Hospital and University of Iceland School of Medicine
- Daniel Barrowdale
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Lars Beckmann
- Institute for Quality and Efficiency in Health Care (IQWiG)
- Matthias W. Beckmann
- Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN
- Javier Benitez
- Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO)
- Stephanie V. Blank
- NYU Women’s Cancer Program, New York University School of Medicine
- Carl Blomqvist
- Department of Oncology, University of Helsinki and Helsinki University Central Hospital
- Natalia V. Bogdanova
- Department of Radiation Oncology, Hannover Medical School
- Stig E. Bojesen
- Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital
- Manjeet K. Bolla
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Bernardo Bonanni
- Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia
- Hiltrud Brauch
- Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology
- Hermann Brenner
- Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ)
- Barbara Burwinkel
- Department of Obstetrics and Gynecology, University of Heidelberg
- Saundra S. Buys
- Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine
- Trinidad Caldes
- Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC
- Maria A. Caligo
- Department of Laboratory Medicine, Section of Genetic Oncology, University and University Hospital of Pisa
- Federico Canzian
- Genomic Epidemiology Group, German Cancer Research Center (DKFZ)
- Jane Carpenter
- Australian Breast Cancer Tissue Bank, Westmead Millennium Institute, University of Sydney
- Jenny Chang-Claude
- Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)
- Stephen J. Chanock
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- Wendy K. Chung
- Departments of Pediatrics and Medicine, Columbia University
- Kathleen B. M. Claes
- Center for Medical Genetics, Ghent University
- Angela Cox
- Department of Oncology, Sheffield Cancer Research Centre, University of Sheffield
- Simon S. Cross
- Department of Neuroscience, Academic Unit of Pathology, University of Sheffield
- Julie M. Cunningham
- Department of Laboratory Medicine and Pathology, Mayo Clinic
- Kamila Czene
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Mary B. Daly
- Department of Clinical Genetics, Fox Chase Cancer Center
- Francesca Damiola
- INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon
- Hatef Darabi
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Miguel de la Hoya
- Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC
- Peter Devilee
- Department of Human Genetics and Department of Pathology, Leiden University Medical Center
- Orland Diez
- Oncogenetics Group, University Hospital Vall d’Hebron, Vall d’Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona
- Yuan C. Ding
- Department of Population Sciences, Beckman Research Institute of City of Hope
- Riccardo Dolcetti
- Cancer Bioimmunotherapy Unit, CRO Aviano National Cancer Institute
- Susan M. Domchek
- Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania
- Cecilia M. Dorfling
- Department of Genetics, University of Pretoria
- Isabel dos-Santos-Silva
- Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine
- Martine Dumont
- Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University
- Alison M. Dunning
- Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Diana M. Eccles
- Faculty of Medicine, University of Southampton, University Hospital Southampton
- Hans Ehrencrona
- Department of Immunology, Genetics and Pathology, Uppsala University
- Arif B. Ekici
- Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg
- Heather Eliassen
- Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School
- Steve Ellis
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Peter A. Fasching
- Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN
- Jonine Figueroa
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- Dieter Flesch-Janys
- Department of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf
- Asta Försti
- Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ)
- Florentia Fostira
- Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research ‘Demokritos’, Aghia Paraskevi Attikis
- William D. Foulkes
- Program in Cancer Genetics, McGill University
- Tara Friebel
- University of
- Eitan Friedman
- Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center
- Debra Frost
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Marike Gabrielson
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Marilie D. Gammon
- Department of Epidemiology, University of
- Patricia A. Ganz
- Division of Cancer Prevention and Control Research, UCLA Schools of Medicine and Public Health, Jonsson Comprehensive Cancer Center
- Susan M. Gapstur
- Epidemiology Research Program, American Cancer Society
- Judy Garber
- Cancer Risk and Prevention Clinic, Dana Farber Cancer Institute
- Mia M. Gaudet
- Epidemiology Research Program, American Cancer Society
- Simon A. Gayther
- Department of Biomedical Sciences, Cedars Sinai Medical Center
- Anne-Marie Gerdes
- Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital
- Maya Ghoussaini
- Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Graham G. Giles
- Cancer Epidemiology Centre, Cancer Council Victoria
- Gord Glendon
- Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital
- Andrew K. Godwin
- Department of Pathology and Laboratory Medicine, University of Kansas Medical Center
- Mark S. Goldberg
- Department of Medicine, McGill University
- David E. Goldgar
- Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine
- Anna González-Neira
- Human Genotyping-CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO)
- Mark H. Greene
- Division of Cancer Epidemiology and Genetics, Clinical Genetics Branch, National Cancer Institute, National Institutes of Health
- Jacek Gronwald
- Department of Genetics and Pathology, Pomeranian Medical University
- Pascal Guénel
- Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer
- Marc Gunter
- Department of of Epidemiology and Biostatistics, School of Public Health, Imperial College London
- Lothar Haeberle
- Department of Gynecology and Obstetrics, University Breast Center Franconia, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN
- Christopher A. Haiman
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center
- Ute Hamann
- Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)
- Thomas V. O. Hansen
- Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital
- Steven Hart
- Department of Health Sciences Research, Mayo Clinic
- Sue Healey
- Department of Genetics, QIMR Berghofer Medical Research Institute
- Tuomas Heikkinen
- Department of Obstetrics and Gynecology, University of Heidelberg
- Brian E. Henderson
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center
- Josef Herzog
- Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network
- Frans B. L. Hogervorst
- Family Cancer Clinic, Netherlands Cancer Institute
- Antoinette Hollestelle
- Department of Medical Oncology, Erasmus MC Cancer Institute
- Maartje J. Hooning
- Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center
- Robert N. Hoover
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- John L. Hopper
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne
- Keith Humphreys
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- David J. Hunter
- Program in Molecular and Genetic Epidemiology, Harvard School of Public Health
- Tomasz Huzarski
- Department of Genetics and Pathology, Pomeranian Medical University
- Evgeny N. Imyanitov
- N.N. Petrov Institute of Oncology
- Claudine Isaacs
- Lombardi Comprehensive Cancer Center, Georgetown University
- Anna Jakubowska
- Department of Genetics and Pathology, Pomeranian Medical University
- Paul James
- Familial Cancer Centre, Peter MacCallum Cancer Centre
- Ramunas Janavicius
- State Research Institute Centre for Innovative Medicine
- Uffe Birk Jensen
- Department of Clinical Genetics, Aarhus University Hospital
- Esther M. John
- Department of Epidemiology, Cancer Prevention Institute of California
- Michael Jones
- Division of Genetics and Epidemiology, Institute of Cancer Research
- Maria Kabisch
- Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ)
- Siddhartha Kar
- Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Beth Y. Karlan
- Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
- Sofia Khan
- Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital
- Kay-Tee Khaw
- Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory
- Muhammad G. Kibriya
- Department of Health Studies, The University of Chicago
- Julia A. Knight
- Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital
- Yon-Dschun Ko
- Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus
- Irene Konstantopoulou
- Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research ‘Demokritos’, Aghia Paraskevi Attikis
- Veli-Matti Kosma
- School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland
- Vessela Kristensen
- Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet
- Ava Kwong
- The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital
- Yael Laitman
- Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center
- Diether Lambrechts
- Vesalius Research Center, VIB
- Conxi Lazaro
- Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology
- Eunjung Lee
- Department of Preventive Medicine, University of Southern California
- Loic Le Marchand
- Cancer Epidemiology Program, University of Cancer Center
- Jenny Lester
- Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
- Annika Lindblom
- Department of Molecular Medicine and Surgery, Karolinska Institutet
- Noralane Lindor
- Health Sciences Research, Mayo Clinic
- Sara Lindstrom
- Department of Epidemiology, Harvard School of Public Health
- Jianjun Liu
- Human Genetics Division, Genome Institute of Singapore
- Jirong Long
- Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine
- Jan Lubinski
- Department of Genetics and Pathology, Pomeranian Medical University
- Phuong L. Mai
- Division of Cancer Epidemiology and Genetics, Clinical Genetics Branch, National Cancer Institute, National Institutes of Health
- Enes Makalic
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne
- Kathleen E. Malone
- Division of Public Health Sciences, Fred Hutchinson Cancer Research Center
- Arto Mannermaa
- School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland
- Siranoush Manoukian
- Department of Preventive and Predictive Medicine, Unit of Medical Genetics, Fondazione IRCCS Istituto Nazionale Tumori (INT)
- Sara Margolin
- Department of Oncology, Karolinska University Hospital
- Frederik Marme
- Department of Obstetrics and Gynecology, University of Heidelberg
- John W. M. Martens
- Department of Medical Oncology, Erasmus MC Cancer Institute
- Lesley McGuffog
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Alfons Meindl
- Department of Gynaecology and Obstetrics, Technical University of Munich
- Austin Miller
- NRG Oncology Statistics and Data Management Center, Roswell Park Cancer Institute
- Roger L. Milne
- Cancer Epidemiology Centre, Cancer Council Victoria
- Penelope Miron
- Department of Genomics and Genome Sciences, Case Western Reserve University Medical School
- Marco Montagna
- Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV—IRCCS
- Sylvie Mazoyer
- INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon
- Anna M. Mulligan
- Laboratory Medicine Program, University Health Network
- Taru A. Muranen
- Department of Obstetrics and Gynecology, University of Heidelberg
- Katherine L. Nathanson
- Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania
- Susan L. Neuhausen
- Department of Population Sciences, Beckman Research Institute of City of Hope
- Heli Nevanlinna
- Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital
- Børge G. Nordestgaard
- Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital
- Robert L. Nussbaum
- Invitae Corporation
- Kenneth Offit
- Department of Medicine, Memorial Sloan-Kettering Cancer Center
- Edith Olah
- Department of Molecular Genetics, National Institute of Oncology
- Olufunmilayo I. Olopade
- Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center
- Janet E. Olson
- Department of Health Sciences Research, Mayo Clinic
- Ana Osorio
- Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO)
- Sue K. Park
- Department of Preventive Medicine and Biomedical Science, Seoul National University College of Medicine and Cancer Research Institute, Seoul National University
- Petra H. Peeters
- Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center
- Bernard Peissel
- Department of Preventive and Predictive Medicine, Unit of Medical Genetics, Fondazione IRCCS Istituto Nazionale Tumori (INT)
- Paolo Peterlongo
- IFOM, Fondazione Istituto FIRC di Oncologia Molecolare
- Julian Peto
- Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine
- Catherine M. Phelan
- Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute
- Robert Pilarski
- Department of Internal Medicine, Divison of Human Genetics, The Comprehensive Cancer Center, The Ohio State University
- Bruce Poppe
- Center for Medical Genetics, Ghent University
- Katri Pylkäs
- Department of Clinical Chemistry and Biocenter Oulu, Laboratory of Cancer Genetics and Tumor Biology, University of Oulu, NordLab Oulu/Oulu University Hospital
- Paolo Radice
- Department of Preventive and Predictive Medicine, Unit of Molecular Bases of Genetic Risk and Genetic Testing, Fondazione IRCCS Istituto Nazionale Tumori (INT)
- Nazneen Rahman
- Section of Cancer Genetics, Institute of Cancer Research
- Johanna Rantala
- Department of Clinical Genetics, Karolinska University Hospital
- Christine Rappaport
- Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna
- Gad Rennert
- Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. Rappaport Faculty of Medicine
- Andrea Richardson
- Department of Pathology, Johns Hopkins University School of Medicine
- Mark Robson
- Department of Medicine, Memorial Sloan-Kettering Cancer Center
- Isabelle Romieu
- International Agency for Research on Cancer
- Anja Rudolph
- Division of Cancer Epidemiology, German Cancer Research Center (DKFZ)
- Emiel J. Rutgers
- Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital
- Maria-Jose Sanchez
- Escuela Andaluza de Salud Pública. Instituto de Investigación Biosanitaria ibs.GRANADA, Hospitales Universitarios de Granada/Universidad de Granada
- Regina M. Santella
- Department of Environmental Health Sciences, Columbia University
- Elinor J. Sawyer
- Division of Cancer Studies, Research Oncology, King's College London, Guy’s Hospital
- Daniel F. Schmidt
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne
- Marjanka K. Schmidt
- Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital
- Rita K. Schmutzler
- Center for Hereditary Breast and Ovarian Cancer, Medical Faculty, University Hospital Cologne
- Fredrick Schumacher
- Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center
- Rodney Scott
- Division of Genetics, Hunter Area Pathology Service, John Hunter Hospital
- Leigha Senter
- Department of Internal Medicine, Divison of Human Genetics, The Comprehensive Cancer Center, The Ohio State University
- Priyanka Sharma
- Department of Hematology and Oncology, University of Kansas Medical Center
- Jacques Simard
- Centre Hospitalier Universitaire de Québec Research Center, Laval University
- Christian F. Singer
- Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna
- Olga M. Sinilnikova
- INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon
- Penny Soucy
- Centre Hospitalier Universitaire de Québec Research Center, Laval University
- Melissa Southey
- Department of Pathology, The University of Melbourne
- Doris Steinemann
- Hannover Medical School
- Marie Stenmark-Askmalm
- Division of Clinical Genetics, Department of Clinical and Experimental Medicine, Linköping University
- Dominique Stoppa-Lyonnet
- Department of Tumour Biology, Institut Curie
- Anthony Swerdlow
- Division of Genetics and Epidemiology, Institute of Cancer Research
- Csilla I. Szabo
- National Human Genome Research Institute, National Institutes of Health
- Rulla Tamimi
- Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School
- William Tapper
- Faculty of Medicine, University of Southampton, University Hospital Southampton
- Manuel R. Teixeira
- Department of Genetics, Portuguese Oncology Institute
- Soo-Hwang Teo
- Cancer Research Initiatives Foundation, Sime Darby Medical Centre
- Mary B. Terry
- Department of Epidemiology, Mailman School of Public Health, Columbia University
- Mads Thomassen
- Department of Clinical Genetics, Odense University Hospital
- Deborah Thompson
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Laima Tihomirova
- Latvian Biomedical Research and Study Centre
- Amanda E. Toland
- Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University
- Robert A. E. M. Tollenaar
- Department of Surgical Oncology, Leiden University Medical Center
- Ian Tomlinson
- Wellcome Trust Centre for Human Genetics and Oxford Biomedical Research Centre, University of Oxford
- Thérèse Truong
- Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer
- Helen Tsimiklis
- Department of Pathology, The University of Melbourne
- Alex Teulé
- Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology
- Rosario Tumino
- Cancer Registry and Histopathology Unit, ‘Civic—M.P. Arezzo’ Hospital
- Nadine Tung
- Department of Medical Oncology, Beth Israel Deaconess Medical Center
- Clare Turnbull
- Section of Cancer Genetics, Institute of Cancer Research
- Giski Ursin
- Cancer Registry of Norway, Institute of Population-Based Cancer Research
- Carolien H. M. van Deurzen
- Department of Pathology, Family Cancer Clinic, Erasmus University Medical Center
- Elizabeth J. van Rensburg
- Department of Genetics, University of Pretoria
- Raymonda Varon-Mateeva
- Institute of Human Genetics, Charite Berlin
- Zhaoming Wang
- Division of Cancer Epidemiology and Genetics, Cancer Genomics Research Laboratory, National Cancer Institute
- Shan Wang-Gohrke
- University Hospital Ulm
- Elisabete Weiderpass
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Jeffrey N. Weitzel
- Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network
- Alice Whittemore
- Department of Health Research and Policy—Epidemiology, Stanford University School of Medicine
- Hans Wildiers
- Department of General Medical Oncology, Multidisciplinary Breast Center, University Hospitals
- Robert Winqvist
- Department of Clinical Chemistry and Biocenter Oulu, Laboratory of Cancer Genetics and Tumor Biology, University of Oulu, NordLab Oulu/Oulu University Hospital
- Xiaohong R. Yang
- Division of Cancer Epidemiology and Genetics, National Cancer Institute
- Drakoulis Yannoukakos
- Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research ‘Demokritos’, Aghia Paraskevi Attikis
- Song Yao
- Department of Cancer Prevention and Control, Roswell Park Cancer Institute
- M Pilar Zamora
- Servicio de Oncología Médica, Hospital Universitario La Paz
- Wei Zheng
- Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine
- Per Hall
- Department of Medical Epidemiology and Biostatistics, Karolinska Institutet
- Peter Kraft
- Department of Epidemiology, Harvard School of Public Health
- Celine Vachon
- Department of Health Sciences Research, Mayo Clinic
- Susan Slager
- Department of Health Sciences Research, Mayo Clinic
- Georgia Chenevix-Trench
- Cancer Division, QIMR Berghofer Medical Research Institute
- Paul D. P. Pharoah
- Department of Oncology, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Alvaro A. N. Monteiro
- Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute
- Montserrat García-Closas
- Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health
- Douglas F. Easton
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- Antonis C. Antoniou
- Department of Public Health and Primary Care, Centre for Cancer Genetic Epidemiology, University of Cambridge
- DOI
- https://doi.org/10.1038/ncomms11375
- Journal volume & issue
-
Vol. 7,
no. 1
pp. 1 – 13
Abstract
Oestrogen negative breast cancer is associated with a poor prognosis. In this study, the authors perform a meta-analysis of 11 breast cancer genome-wide association studies and identify four new loci associated with oestrogen negative breast cancer risk. These findings may aid in stratifying patients in the clinic.
