Frontiers in Endocrinology (Oct 2022)

Positive association between weight-adjusted-waist index and hyperuricemia in patients with hypertension: The China H-type hypertension registry study

  • Peixu Zhao,
  • Peixu Zhao,
  • Peixu Zhao,
  • Weidong Shi,
  • Yumeng Shi,
  • Yumeng Shi,
  • Yumeng Shi,
  • Yurong Xiong,
  • Yurong Xiong,
  • Yurong Xiong,
  • Congcong Ding,
  • Congcong Ding,
  • Congcong Ding,
  • Xiaoli Song,
  • Xiaoli Song,
  • Xiaoli Song,
  • Guosheng Qiu,
  • Guosheng Qiu,
  • Guosheng Qiu,
  • Junpei Li,
  • Junpei Li,
  • Junpei Li,
  • Wei Zhou,
  • Wei Zhou,
  • Wei Zhou,
  • Chao Yu,
  • Chao Yu,
  • Chao Yu,
  • Tao Wang,
  • Tao Wang,
  • Tao Wang,
  • Lingjuan Zhu,
  • Lingjuan Zhu,
  • Lingjuan Zhu,
  • Xiaoshu Cheng,
  • Xiaoshu Cheng,
  • Xiaoshu Cheng,
  • Huihui Bao,
  • Huihui Bao,
  • Huihui Bao

DOI
https://doi.org/10.3389/fendo.2022.1007557
Journal volume & issue
Vol. 13

Abstract

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Background and aimsThe relationship between the new obesity index weight-adjusted-waist index (WWI) and hyperuricemia is unclear. We aimed to explore the association of the WWI and hyperuricemia among the hypertensive population.MethodsA total of 14,078 hypertension participants with complete data were included in our study. WWI was calculated by waist circumference divided by the square root of weight. Specifically, men with 420 μmol/L and women with 360 μmol/L were considered to have hyperuricemia.ResultsThe prevalence of hyperuricemia was 61.1% in men and 51.4% in women. On the whole, multivariate logistic regression analyses found that there was a linear positive correlation of WWI with hyperuricemia in both men (OR: 1.37; 95%CI: 1.25, 1.49) and women (OR: 1.35; 95%CI: 1.26, 1.45). Subgroup analysis found that the relationship between WWI and hyperuricemia was stable in stratified subgroups (all P-interactions >.05).ConclusionWWI showed a positive association with hyperuricemia among hypertension patients.

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